Toxicology of essential and xenobiotic metals / editors João Batista Teixeira da Rocha, Departamento de Bioquímica, ICBS, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil and Departamento de Bioquímica e Biologia Molecular, CCNE, Universidade Federal de Santa Maria, RS, Brazil, Michael Aschner, Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, USA, Pablo Andrei Nogara, Federal Institute of Education, Science and Technology Sul-rio-grandense (IFSul), Bagé, RS, Brazil.
| Other author | Da Rocha, João Batista Teixeira, 1964- |
| Other author | Aschner, Michael, 1955- |
| Other author | Nogara, Pablo Andrei, 1991- |
| Format | Electronic |
| Edition | First edition. |
| Publication Info | Boca Raton : CRC Press, Taylor & Francis Group, 2025. |
| Description | vi, 250 pages ; 24 cm |
| Supplemental Content | Full text available from eBooks on EBSCOhost |
| Subjects |
| Partial contents | Zebrafish as a model organism to study manganese toxicity / Nilda Vargas Barbosa, Sabrina Antunes Ferreira and Matheus Mülling dos Santos -- The influence of tellurium and selenium compounds in biological systems and selenium (Se) and tellurium (Te) toxicity / Silvia Vávrová, Eva Struhárňanská, Ján Turňa and Stanislav Stuchlík. |
| Abstract | "The toxicology of metals is a global concern. Metals exposure induces toxic manifestations by acute or chronic pathologies. Heavy metals such as arsenic (As), cadmium (Cd), mercury (Hg), thallium (Tl), and lead (Pb), are known for their enormous toxicity. Generally, the symptoms of metal intoxication depend upon the type (chemical species), dose, method, and duration of exposure. In an acute metal exposure, the immediate vital signs include nausea, vomiting, diarrhea, and abdominal pain. Humans' and animals' long-term chronic exposure to heavy metals and metalloids can lead to numerous physical, muscular, neurological, nephrological, and diverse degenerative diseases and dysfunctions, including multiple sclerosis, muscular dystrophy, cardiovascular disorders, Parkinson's, and Alzheimer's diseases. The understanding of the metals' interactions with target proteins is essential to identify their metabolism, distribution, and toxicity. The modulation of the redox biology status by metals is a critical point in its toxicological action. Mercury has been identified as the most toxic heavy metal, and its poisoning is known as acrodynia or pink disease. The development of analytical sensitivity techniques and methodologies to detect very small amounts of some toxic metals (Pb and Hg), at the molecular level, is essential. The data described in this book is intended to be a reference for health professionals and students of toxicology"-- Provided by publisher. |
| General note | "A science publishers book." |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2024031862 |
| ISBN | 9781032292281 (hbk) |
| ISBN | 9781032292298 (pbk) |
| ISBN | (ebk) |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |