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010 a| 2023004854;

020 a| 9781032004068q| (hardback);

020 a| 9781032004099q| (paperback);

020 z| 9781003174028q| (ebook);

035 a| (WaSeSS)ssj0002865546;

042 a| pcc;

049 a| EREEa| NEHH;

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082 00 a| 572.8/82| 23/eng/20230503;

245 00 a| RNA-seq in drug discovery and developmenth| [electronic resource] /c| edited by Feng Cheng, Robert Morris.;

250 a| First edition.;

260 a| Boca Raton :b| CRC Press,c| 2023.;

263 a| 2307;

300 a| pages cm;

490 1 a| Drugs and the pharmaceutical sciences series;

504 a| Includes bibliographical references and index.;

505 0 a| Introduction to RNA-Sequencing and Quality Control / Feng Cheng and Robert Morris -- Read Alignment and Transcriptome Assembly / Feng Cheng and Robert Morris -- Normalization and Downstream Analyses / Feng Cheng and Robert Morris -- Constitutive and Alternative Splicing Events / Feng Cheng and Robert Morris -- The role of transcriptomics in identifying fusion genes and chimeric RNAs in cancer / Feng Cheng, Valeria Zuluaga and Robert Morris -- MiRNA and RNA-seq / Feng Cheng and Robert Morris -- Toxicogenomics and RNA-seq / Robert Morris, Kyle Eckhoff, Rebecca Polsky, and Feng Chen -- Drug Discovery and Traditional Medicine / Feng Cheng and Robert Morris -- Single-Cell RNA-sequencing / Feng Cheng and Robert Morris.;

506 a| Available only to authorized users.;

520 a| "The research and development process in modern drug discovery and development is a complex and challenging task. Using traditional biological test methods such as PCR to measure the expression levels or function of these genes is costly and time-consuming. RNA-seq can measure the expression patterns of thousands of genes simultaneously and provide insights into functional pathways or regulations in biological processes, which has revolutionized the way biological scientists examine gene functions. This book addresses the various aspects of the RNA-seq technique, especially its application in drug discovery and development"--c| Provided by publisher.;

538 a| Mode of access: World Wide Web;

650 12 a| Sequence Analysis, RNAx| methods=| ^A933521;

650 22 a| Drug Discoveryx| methods=| ^A1023263;

650 22 a| Computational Biologyx| methods=| ^A932025;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Cheng, Fengc| (Computational biologist)?| UNAUTHORIZED;

700 1 a| Morris, Robertc| (Of University of South Florida)?| UNAUTHORIZED;

830 0 a| Drugs and the pharmaceutical sciences.x| 0360-2583=| ^A800938;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3634862&scope=site&custid=s5822723&authtype=ip,shib;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6782694-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 7/20/2026x| EBOOKz| JERESOURCE;

RNA-seq in drug discovery and development / edited by Feng Cheng, Robert Morris.

Other author	Cheng, Feng (Computational biologist)
Other author	Morris, Robert (Of University of South Florida)
Format	Electronic
Edition	First edition.
Publication Info	Boca Raton : CRC Press, 2023.
Description	pages cm
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	Sequence Analysis, RNA--methods. Drug Discovery--methods. Computational Biology--methods.

Series	Drugs and the pharmaceutical sciences series Drugs and the pharmaceutical sciences. 0360-2583 ^A800938
Contents	Introduction to RNA-Sequencing and Quality Control / Feng Cheng and Robert Morris -- Read Alignment and Transcriptome Assembly / Feng Cheng and Robert Morris -- Normalization and Downstream Analyses / Feng Cheng and Robert Morris -- Constitutive and Alternative Splicing Events / Feng Cheng and Robert Morris -- The role of transcriptomics in identifying fusion genes and chimeric RNAs in cancer / Feng Cheng, Valeria Zuluaga and Robert Morris -- MiRNA and RNA-seq / Feng Cheng and Robert Morris -- Toxicogenomics and RNA-seq / Robert Morris, Kyle Eckhoff, Rebecca Polsky, and Feng Chen -- Drug Discovery and Traditional Medicine / Feng Cheng and Robert Morris -- Single-Cell RNA-sequencing / Feng Cheng and Robert Morris.
Abstract	"The research and development process in modern drug discovery and development is a complex and challenging task. Using traditional biological test methods such as PCR to measure the expression levels or function of these genes is costly and time-consuming. RNA-seq can measure the expression patterns of thousands of genes simultaneously and provide insights into functional pathways or regulations in biological processes, which has revolutionized the way biological scientists examine gene functions. This book addresses the various aspects of the RNA-seq technique, especially its application in drug discovery and development"-- Provided by publisher.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2023004854
ISBN	9781032004068 (hardback)
ISBN	9781032004099 (paperback)
ISBN	(ebook)

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RNA-seq in drug discovery and development / edited by Feng Cheng, Robert Morris.

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