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020 a| 9783319290713q| hardback ; alk. paper;

020 a| 3319290711q| hardback ; alk. paper;

020 z| 9783319290737q| electronic book;

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245 00 a| RNA processingh| [electronic resource] :b| disease and genome-wide probing /c| Gene W. Yeo, editor.;

260 a| [Cham] Switzerland :b| Springer,c| [2016];

300 a| xiii, 326 pages :b| illustrations (chiefly color) ;c| 25 cm.;

490 1 a| Advances in experimental medicine and biology,x| 0065-2598 ;v| volume 907;

504 a| Includes bibliographical references and index.;

505 0 a| Experimental and computational considerations in the study of RNA binding protein-RNA interactions -- Genome-wide approaches for RNA structure probing -- Tethered function assays as tools to elucidate the molecular roles of RNA binding proteins -- Single molecule approaches in RNA-protein interactions -- RNA dynamics in the control of circadian rhythm -- Roles of RNA binding proteins and post-transcriptional regulation in driving male germ cell development in the mouse -- Regulation of stem cell self-renewal and oncogenesis by RNA binding proteins -- Controlling the editor : the many roles of RNA binding proteins in regulating A-to-I RNA editing -- Mutations in splicing factors and cancer -- Regulation of tissue-specific alternative splicing : C. elegans as a model system -- RNA granules and diseases -- A case study of stress granules in ALS and FTLD -- Post-translational modifications and RNA-binding proteins.;

506 a| Available only to authorized users.;

520 a| "Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm"--Back cover.;

538 a| Mode of access: World Wide Web;

650 12 a| RNA-Binding Proteins0| https://id.nlm.nih.gov/mesh/D016601;

650 22 a| RNA Splicing0| https://id.nlm.nih.gov/mesh/D012326;

650 22 a| RNA Processing, Post-Transcriptional0| https://id.nlm.nih.gov/mesh/D012323;

650 22 a| Systems Biologyx| methods0| https://id.nlm.nih.gov/mesh/D049490Q000379;

650 22 a| Carcinogenesisx| genetics0| https://id.nlm.nih.gov/mesh/D063646Q000235;

655 0 a| Electronic books.;

700 1 a| Yeo, Gene W.;

830 0 a| Advances in experimental medicine and biology ;v| v. 907.x| 0065-2598;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1175585&scope=site&custid=s5822723&authtype=ip,shib;

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RNA processing disease and genome-wide probing / Gene W. Yeo, editor.

Other author	Yeo, Gene W.
Format	Electronic
Publication Info	[Cham] Switzerland : Springer, [2016]
Description	xiii, 326 pages : illustrations (chiefly color) ; 25 cm.
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	RNA-Binding Proteins RNA Splicing RNA Processing, Post-Transcriptional Systems Biology--methods. Carcinogenesis--genetics.

Series	Advances in experimental medicine and biology, 0065-2598 ; volume 907 Advances in experimental medicine and biology ; v. 907. 0065-2598
Contents	Experimental and computational considerations in the study of RNA binding protein-RNA interactions -- Genome-wide approaches for RNA structure probing -- Tethered function assays as tools to elucidate the molecular roles of RNA binding proteins -- Single molecule approaches in RNA-protein interactions -- RNA dynamics in the control of circadian rhythm -- Roles of RNA binding proteins and post-transcriptional regulation in driving male germ cell development in the mouse -- Regulation of stem cell self-renewal and oncogenesis by RNA binding proteins -- Controlling the editor : the many roles of RNA binding proteins in regulating A-to-I RNA editing -- Mutations in splicing factors and cancer -- Regulation of tissue-specific alternative splicing : C. elegans as a model system -- RNA granules and diseases -- A case study of stress granules in ALS and FTLD -- Post-translational modifications and RNA-binding proteins.
Abstract	"Ribonucleic acid (RNA) binding proteins currently number in the thousands and defects in their function are at the heart of diseases such as cancer and neurodegeneration. RNA binding proteins have become implicated in the intricate control of surprisingly diverse biological settings, such as circadian rhythm, stem cell self-renewal, oncogenesis and germ cell development. This book surveys a range of genome-wide and systems approaches to studying RNA binding proteins, the importance of RNA binding proteins in development, cancer and circadian rhythm"--Back cover.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2016936562
ISBN	9783319290713 hardback ; alk. paper
ISBN	3319290711 hardback ; alk. paper
ISBN	electronic book
ISBN	electronic book

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