Leydig cells structure, functions and clinical aspects / [edited by Bruno Solomon].

Other author Solomon, Bruno.
Format Electronic
Publication InfoNew York : Nova Science Publishers, Inc., [2019]
Descriptionpages cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

SeriesCell biology research progress
Contents Immunological function of leydig cells / Ran Chen, Fei Wang and Daishu Han -- Leydig cell lines : in vitro models for testosterone biosynthesis / NeBahat Yildizbayrak and Melike Erkan -- the role of environmental contaminants in leydig cell steroidogenesis / Banu Orta Yilmaz and Melike Erkan -- Effect of endocrine disruptors (PCBs/DEHP) on testicular leydig cells in adult and F1 male offspring rats / J. Arunakaran.
Abstract "The main function of the Leydig cells is to synthesize testosterone, but growing evidence supports the idea that Leydig cells are important in regulating the testicular immune environment. As such, Leydig Cells: Structure, Functions and Clinical Aspects discusses Leydig cells serving as immunological sentinels in the testis. Next, the authors explore the commercially available immortalized Leydig cell lines (TM3, R2C, MA-10 and MLTC-1) derived from rat or mouse and the results of studies using these cells. Additionally, the effects of the most commonly used environmental contaminants on Leydig cell function are discussed in the context of the impaired of steroidogenic pathway. The results of several studies are presented which demonstrate that lycopene supplementation improves and maintains the normal level of testosterone by improving the expression of StAR protein and steroidogenic enzymes in the Leydig cells of polychlorinated biphenyl exposed rats"-- Provided by publisher.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2019059717
ISBN9781536172829 (paperback)
ISBN(adobe pdf)

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