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020 a| 9781493935079q| (hardback)q| (alk. paper);

020 a| 1493935070q| (hardback)q| (alk. paper);

020 z| 9781493935093q| (eBook);

020 z| 1493935097q| (eBook);

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245 00 a| Genome editingh| [electronic resource] :b| the next step in gene therapy /c| Toni Cathomen, Matthew Hirsch, Matthew Porteus, editors.;

260 a| New York :b| Springer,c| [2016];

300 a| xvi, 263 pages :b| illustrations (chiefly color) ;c| 25 cm.;

490 1 a| Advances in experimental medicine and biology,x| 0065-2598 ;v| volume 895.a| American Society of Gene & Cell Therapy;

500 a| "American Society of Gene & Cell Therapy"--Cover.;

504 a| Includes bibliographical references and index.;

505 0 a| Gene editing 20 years later / Maria Jasin -- The development and use of zinc-finger nucleases / Dana Carroll -- The use and development of TAL effector nucleases / Alexandre Juillerat, Philippe Duchateau, Toni Cathomen, and Claudio Mussolino -- Genome editing for neuromuscular diseases / David G. Ousterout and Charles A. Gersbach -- Phage integrases for genome editing / Michele P. Calos -- Precise genome modification using triplex forming oligonucleotides and peptide nucleic acids / Raman Bahal, Anisha Gupta, and Peter M. Glazer -- Genome editing by Aptamer-Guided Gene Targeting (AGT) / Patrick Ruff and Francesca Storici -- Stimulation of AAV gene editing via DSB repair / Angela M. Mitchell, Rachel Moser, Richard Jude Samulski, and Matthew Louis Hirsch -- Engineered nucleases and trinucleotide repeat diseases / John H. Wilson, Christopher Moye, and David Mittelman -- Using engineered nucleases to create HIV- resistant cells / George Nicholas Llewellyn, Colin M. Exline, Nathalia Holt, and Paula M. Cannon -- Strategies to determine off-target effects of engineered nucleases / Eli J. Fine, Thomas James Cradick, and Gang Bao -- Cellular engineering and disease modeling with gene-editing nucleases / Mark J. Osborn and Jakub Tolar.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Genetic engineering.;

650 0 a| Gene therapy.;

650 12 a| Genetic Engineering;

650 22 a| Genome, Humanx| genetics;

650 7 a| Gene therapy2| fast0| (OCoLC)fst00939638;

650 7 a| Genetic engineering.2| fast0| (OCoLC)fst00940027;

655 0 a| Electronic books.;

700 1 a| Cathomen, Toni.;

700 1 a| Hirsch, Matthew.;

700 1 a| Porteus, Matthew H.;

710 2 a| American Society of Gene & Cell Therapy.;

830 0 a| Advances in experimental medicine and biology ;v| v. 895.x| 0065-2598;

830 0 a| Advances in experimental medicine and biology.p| American Society of Gene & Cell Therapy.;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=1174610&scope=site&custid=s5822723&authtype=ip,shib;

947 a| (OCoLC)ocn927376089;

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998 a| 6759113;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6759113-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 7/17/2026x| EBOOKz| JERESOURCE;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6759113-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 7/17/2026x| EBOOKz| JERESOURCE;

Genome editing the next step in gene therapy / Toni Cathomen, Matthew Hirsch, Matthew Porteus, editors.

Format	Electronic
Publication Info	New York : Springer, [2016]
Description	xvi, 263 pages : illustrations (chiefly color) ; 25 cm.
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	Genetic engineering. Gene therapy. Genetic Engineering Genome, Human--genetics.

Other author/creator	Cathomen, Toni.
Other author/creator	Hirsch, Matthew.
Other author/creator	Porteus, Matthew H.
Other author/creator	American Society of Gene & Cell Therapy.
Series	Advances in experimental medicine and biology, 0065-2598 ; volume 895. American Society of Gene & Cell Therapy Advances in experimental medicine and biology ; v. 895. 0065-2598 Advances in experimental medicine and biology. American Society of Gene & Cell Therapy.
Contents	Gene editing 20 years later / Maria Jasin -- The development and use of zinc-finger nucleases / Dana Carroll -- The use and development of TAL effector nucleases / Alexandre Juillerat, Philippe Duchateau, Toni Cathomen, and Claudio Mussolino -- Genome editing for neuromuscular diseases / David G. Ousterout and Charles A. Gersbach -- Phage integrases for genome editing / Michele P. Calos -- Precise genome modification using triplex forming oligonucleotides and peptide nucleic acids / Raman Bahal, Anisha Gupta, and Peter M. Glazer -- Genome editing by Aptamer-Guided Gene Targeting (AGT) / Patrick Ruff and Francesca Storici -- Stimulation of AAV gene editing via DSB repair / Angela M. Mitchell, Rachel Moser, Richard Jude Samulski, and Matthew Louis Hirsch -- Engineered nucleases and trinucleotide repeat diseases / John H. Wilson, Christopher Moye, and David Mittelman -- Using engineered nucleases to create HIV- resistant cells / George Nicholas Llewellyn, Colin M. Exline, Nathalia Holt, and Paula M. Cannon -- Strategies to determine off-target effects of engineered nucleases / Eli J. Fine, Thomas James Cradick, and Gang Bao -- Cellular engineering and disease modeling with gene-editing nucleases / Mark J. Osborn and Jakub Tolar.
General note	"American Society of Gene & Cell Therapy"--Cover.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2015958888
ISBN	9781493935079 (hardback) (alk. paper)
ISBN	1493935070 (hardback) (alk. paper)
ISBN	(eBook)
ISBN	(eBook)

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Genome editing the next step in gene therapy / Toni Cathomen, Matthew Hirsch, Matthew Porteus, editors.

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