| Contents |
CRISPR-Cas Systems : The Molecular Scissors / Bashir Ahmad Malla, Aarif Ali, Nuzhat Khursheed, Mohammad Saleem Bhat, Farhat Jabeen, Javeed Iqbal Ahmad Bhat -- Beyond CRISPR-Cas9 System: Other Gene Editing Technologies / Aarif Ali, Mohammad Saleem Bhat, Javeed Iqbal Ahmad Bhat, Sadhna Aggarwal, Sheikh Bilal Ahmad -- CRISPR-Cas Systems in Genetic Diseases / Zainab Manzoor, Umar Rasool, Arshid Reshi, Aarif Ali -- CRISPR-Cas Systems in Agriculture / Farkhanda Jabeen, Noreen Aasim, Farheen Shafique -- CRISPR-Cas Systems in Insects and Other Arthropods / Arjumand John, Amaninder Kaur Riat, Kaisar Ahmad Bhat, Aarif Ali -- CRISPR-Cas Systems in Cancer Biology and Therapeutics / Gh Jeelani Mir, Aarif Ali, Nisar ul Ashraf, Javeed Iqbal Ahmad Bhat, Showkat Ahmad Ganie, Sheikh Bilal Ahmad, Rabia Hamid -- CRISPR-Cas systems in diagnosis of infectious and non-infectious diseases / Aarif Ali, Javeed Iqbal Ahmad Bhat, Farheen Shafique -- CRISPR-Cas Systems in Hemolytic Diseases / Huma Hameed, Mahtab Ahmad Khan, Saleha Faheem, Muhammad Zaman, Tooba Mehboob, Tehseen Riaz, Naila Tabassam -- CRISPR-Cas Systems in Neurological Diseases / Aarif Ali, Bashir Ahmad Malla, Mohammad Saleem Bhat, Javeed Iqbal Ahmad Bhat -- CRISPR-Cas System in Microbes / Tooba Mehboob, Naila Tabassam, Huma Hameed, Muhammad Zaman, Mahtab Ahmad Khan, Imtiaz Majeed, Tehseen Riaz -- Current vectors for in-vivo delivery of CRISPR-Cas9 System / Nausheen Shafi, Tasaduq Manzoor, Irfan Hussain, Junaid Nazir, Aarif Ali, Ubaid Gani, Lateef Ahmad Dar, Yaawar Bashir Mir, Syed Mudasir Ahmad, Meena Godha, Priyanka Jha -- Ethical Issues in Genome Editing / Huma Hameed, Muhammad Zaman, Saleha Faheem, Mahtab Ahmad Khan, Shazia Akram Ghumman, Tooba Mehboob, Naila Tabassam. |
| Abstract |
"CRISPR-Cas systems have redefined the landscape of genetic engineering, offering an unprecedented level of precision, efficiency, and versatility in genome editing. This book entitled "Gene Editing by CRISPR-Cas" provides a comprehensive and well-structured approach on the historical context of genetics and gene editing techniques leading to the ground-breaking discovery of CRISPR-Cas systems. Distinguished by its multidisciplinary scope, this volume not only delves into CRISPR-Cas systems but also examines alternative and next-generation gene-editing technologies. The book aims to inform and engage both general audience with a keen interest in science and biology, as well as professionals and students in related fields. By offering a balanced blend of scientific explanations, real-world applications, the book seeks to empower readers to understand the potential of CRISPR technology and its impact across diverse domains such as medicine, agriculture, biotechnology, and diagnostics, while addressing the ethical, regulatory, and biosafety considerations essential for responsible implementation. Furthermore, this book engages in a discussion on the future directions and broader impacts of CRISPR technologies, providing valuable insights into the evolving landscape of genome engineering and its implications for scientific advancements. Key Features This book is written in a clear and accessible manner, making complex scientific concepts understandable to a general audience without overwhelming them with technical jargon. This book provides a comprehensive exploration of the discovery and evolution of CRISPR technology, delving into the underlying science and its transformative capabilities. It serves as an excellent introduction to both the technical intricacies and the human implications of this groundbreaking technology This book provides an in-depth exploration of the potential uses of CRISPR across multiple domains, with a particular focus on genetic disease treatment, cancer studies, agricultural advancements, HIV, blood disorders, neurological conditions, insect biology, microbial engineering, and both infectious and non-infectious diseases. Furthermore, this book also provides critical analysis of bioethics, safety concerns, and regulatory frameworks, providing a responsible perspective on genome editing"-- Provided by publisher. |
