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010 a| 2016937842;

020 a| 9780128015964q| (paperback);

020 a| 0128015969q| (paperback);

020 z| 9780128017814q| (ebook);

035 a| (WaSeSS)ssj0001832662;

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245 00 a| DNA modifications in the brainh| [electronic resource] :b| neuroepigenetic regulation of gene expression /c| edited by Timothy W. Bredy, Department of Neurobiology and Behavior, The Francisco J. Ayala School of Biological Sciences, Bonney Research Laboratory, University of California Irvine, Irvine, CA, United States.;

260 a| London, United Kingdom :b| Academic Press, is an imprint of Elsevier,c| [2017];

300 a| xi, 167 pages :b| color illustrations ;c| 24 cm;

504 a| Includes bibliographical references and index.;

505 0 a| Preface -- History and modern view on DNA modifications in the brain / B.F. Vanyushin and V.V. Ashapkin -- Approaches to detecting DNA base modification in the brain / X. Li and W. Wei -- Active DNA demethylation in neurodevelopment / Y. Kang, Z. Wang and P. Jin -- TET and 5hmC in neurodevelopment and the adult brain / M. Fasolino, S.A. Welsh and Z. Zhou -- Beyond mCG : DNA methylation in noncanonical sequence context / E.A. Mukamel and R. Lister -- DNA modifications and memory / J.J. Day -- Measuring CpG methylation by SMRT sequencing / Y. Suzuki, J. Korlach and S. Morishita -- Epigenetic modifications of DNA and drug addiction / J. Feng and E.J. Nestler -- What does the future hold for the study of nucleic acid modifications in the brain? / P.R. Marshall and T.W. Bredy.;

506 a| Available only to authorized users.;

520 a| Begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.--c| Source other than the Library of Congress.;

538 a| Mode of access: World Wide Web;

650 0 a| DNA.=| ^A8939;

650 0 a| Genetic transformation.=| ^A137175;

650 0 a| Nucleotide sequence.=| ^A13542;

650 0 a| Gene expression.=| ^A6250;

650 0 a| Brain.=| ^A827;

650 2 a| DNA.0| (DNLM)D004247=| ^A920250;

650 2 a| Transformation, Genetic.0| (DNLM)D014170=| ^A936514;

650 2 a| Base Sequence.0| (DNLM)D001483=| ^A923105;

650 2 a| Gene Expression.0| (DNLM)D015870=| ^A919546;

650 2 a| Brain.0| (DNLM)D001921=| ^A917911;

650 7 a| Brain.2| fast0| (OCoLC)fst00837570;

650 7 a| DNA.2| fast0| (OCoLC)fst00886555;

650 7 a| Gene expression.2| fast0| (OCoLC)fst00939613;

650 7 a| Genetic transformation.2| fast0| (OCoLC)fst00940104;

650 7 a| Nucleotide sequence.2| fast0| (OCoLC)fst01041106;

947 a| (OCoLC)ocn957503525;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Bredy, Timothy W.?| UNAUTHORIZED;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=1144413&scope=site&custid=s5822723&authtype=ip,shib;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6752627-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 7/16/2026x| EBOOKz| JERESOURCE;

DNA modifications in the brain neuroepigenetic regulation of gene expression / edited by Timothy W. Bredy, Department of Neurobiology and Behavior, The Francisco J. Ayala School of Biological Sciences, Bonney Research Laboratory, University of California Irvine, Irvine, CA, United States.

Other author	Bredy, Timothy W.
Format	Electronic
Publication Info	London, United Kingdom : Academic Press, is an imprint of Elsevier, [2017]
Description	xi, 167 pages : color illustrations ; 24 cm
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	DNA. Genetic transformation. Nucleotide sequence. Gene expression. Brain. DNA. Transformation, Genetic. Base Sequence. Gene Expression. Brain.

Contents	Preface -- History and modern view on DNA modifications in the brain / B.F. Vanyushin and V.V. Ashapkin -- Approaches to detecting DNA base modification in the brain / X. Li and W. Wei -- Active DNA demethylation in neurodevelopment / Y. Kang, Z. Wang and P. Jin -- TET and 5hmC in neurodevelopment and the adult brain / M. Fasolino, S.A. Welsh and Z. Zhou -- Beyond mCG : DNA methylation in noncanonical sequence context / E.A. Mukamel and R. Lister -- DNA modifications and memory / J.J. Day -- Measuring CpG methylation by SMRT sequencing / Y. Suzuki, J. Korlach and S. Morishita -- Epigenetic modifications of DNA and drug addiction / J. Feng and E.J. Nestler -- What does the future hold for the study of nucleic acid modifications in the brain? / P.R. Marshall and T.W. Bredy.
Abstract	Begins with an historical overview of the early discoveries surrounding DNA methylation in the mammalian brain and then explores the evidence supporting a role for this epigenetic mechanism in controlling gene expression programs across the lifespan in both normal and diseased states. Chapters describe new directions and technological advances, and provide an overview of what the future holds for this exciting new field. This book is ideal for medical, graduate and advanced undergraduate students, but is also a great resource for researchers who need a broad introduction to the dynamic nature of DNA that sheds light on evolving concepts of gene-environment interaction and their effects on adaptation and neuropsychiatric disease.-- Source other than the Library of Congress.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2016937842
ISBN	9780128015964 (paperback)
ISBN	0128015969 (paperback)
ISBN	(ebook)

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DNA modifications in the brain neuroepigenetic regulation of gene expression / edited by Timothy W. Bredy, Department of Neurobiology and Behavior, The Francisco J. Ayala School of Biological Sciences, Bonney Research Laboratory, University of California Irvine, Irvine, CA, United States.

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