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010 a| 2019056976;

020 a| 9781536169744q| (adobe pdf);

020 z| 9781536169737q| (hardcover);

035 a| (WaSeSS)ssj0002272050;

042 a| pcc;

049 a| EREEa| NEHH;

050 00 a| RC271.P76;

082 00 a| 615.7/982| 23;

245 02 a| A closer look at kinase inhibitionh| [electronic resource] /c| [edited by Alex Tompson].;

260 a| New York :b| Nova Science Publishers, Inc.,c| [2019];

263 a| 2003;

300 a| 1 online resource;

490 0 a| Chemistry research and applications;

504 a| Includes bibliographical references and index.;

505 0 a| Targeted therapy of tyrosine kinase inhibitor drugs for two different cancers (colon-rectal cancer and chronic myelogenous leukemia) and their resistance mechanisms / Gabriella Marfe, Stefania Perna and Carla Di Stefano -- Role of kinases in antiviral therapeutics / Vaishali M. Patil and Neeraj Masand -- In search of novel tau kinase inhibitors and their role in Alzheimer's therapy / Arvind Kumar Jain, Saloni Malla, C. Karthikeyan, Amit K.Tiwari, Piyush Trivedid and Anita Dutt Konara.;

506 a| Available only to authorized users.;

520 a| "A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases, the progress in their use, and the repurposing of approved kinase inhibitors as broad-spectrum antivirals. The key kinases, namely CLK1, DYRK1A, CDK5, GSK3 and CK1, are analyzed as data indicate that targeting these proteins may have therapeutic promise against Alzheimer's disease"--c| Provided by publisher.;

538 a| Mode of access: World Wide Web;

588 a| Description based on print version record and CIP data provided by publisher; resource not viewed.;

650 0 a| Protein-tyrosine kinasex| Inhibitorsx| Therapeutic use.=| ^A1234155;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Tompson, Alex.?| UNAUTHORIZED;

776 08 i| Print version:t| A closer look at kinase inhibitiond| New York : Nova Science Publishers, Inc., [2019]z| 9781536169737w| (DLC) 2019056975;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=6028773;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

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998 a| 6747482;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6747482-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 7/16/2026x| EBOOKz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6747482-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 7/16/2026x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6747482-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 7/16/2026x| EBOOKz| JERESOURCE;

A closer look at kinase inhibition / [edited by Alex Tompson].

Other author	Tompson, Alex.
Format	Electronic
Publication Info	New York : Nova Science Publishers, Inc., [2019]
Description	1 online resource
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Protein-tyrosine kinase--Inhibitors. --Therapeutic use.

Series	Chemistry research and applications
Contents	Targeted therapy of tyrosine kinase inhibitor drugs for two different cancers (colon-rectal cancer and chronic myelogenous leukemia) and their resistance mechanisms / Gabriella Marfe, Stefania Perna and Carla Di Stefano -- Role of kinases in antiviral therapeutics / Vaishali M. Patil and Neeraj Masand -- In search of novel tau kinase inhibitors and their role in Alzheimer's therapy / Arvind Kumar Jain, Saloni Malla, C. Karthikeyan, Amit K.Tiwari, Piyush Trivedid and Anita Dutt Konara.
Abstract	"A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases, the progress in their use, and the repurposing of approved kinase inhibitors as broad-spectrum antivirals. The key kinases, namely CLK1, DYRK1A, CDK5, GSK3 and CK1, are analyzed as data indicate that targeting these proteins may have therapeutic promise against Alzheimer's disease"-- Provided by publisher.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Source of description	Description based on print version record and CIP data provided by publisher; resource not viewed.
Issued in other form	Print version: A closer look at kinase inhibition New York : Nova Science Publishers, Inc., [2019] 9781536169737
Genre/form	Electronic books.
LCCN	2019056976
ISBN	9781536169744 (adobe pdf)
ISBN	(hardcover)

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