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020 a| 9783527349210q| (hardcover);

020 a| 3527349219q| (hardcover);

020 z| 9783527833085q| (ePDF);

020 z| 9783527833108q| (ePub);

020 z| 9783527833092q| (oBook);

035 a| (WaSeSS)ssj0002929233;

042 a| pcc;

044 9| Germany;

049 a| EREEa| NEHH;

050 4 a| QP519.9.C36b| C37 2023;

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245 00 a| Capillary electrophoresis-mass spectrometry for proteomics and metabolomicsh| [electronic resource] :b| principles and applications /c| edited by Rawi Ramautar and David D.Y. Chen.;

260 a| Weinheim, Germany :b| Wiley-VCH,c| [2023];

300 a| xiv, 386 pages :b| color illustrations ;c| 25 cm;

504 a| Includes bibliographical references and index.;

505 0 a| 1. Capillary Electrophoresis-Mass Spectrometry Interfacing: Principles and Recent Developments -- 2. Data Analysis Strategies in CE-MS for Metabolomics -- 3. Data Processing Workflow for Relative Quantification from Label-Free and Isobaric Labeling-Based Untargeted Shotgun Proteomics: From Database Search to Differential Expression Analysis -- 4. Data Processing in Metabolomics Capillary Electrophoresis-Mass Spectrometry -- 5. Utility and Advances of Capillary Electrophoresis-Mass Spectrometry for Metabolomics -- 6. Comprehensive Lipid Profiling by Multisegment Injection-Nonaqueous Capillary Electrophoresis-Mass Spectrometry: Expanding Coverage Beyond Hydrophilic Metabolites -- 7. Strategies for Identification of Modified Amino Acids with CE-MS in Metabolomics -- 8. CE-MS Approaches for Single-Cell Metabolomics -- 9. CE-MS Approaches for Peptidomics -- 10. Capillary Zone Electrophoresis-Mass Spectrometry for Top-Down Proteomics: Technological Development and Biological Applications -- 11. CE-MS Methods for the Characterization of Monoclonal Antibodies -- 12. CE and CE-MS Approaches for Glycan Analysis -- 13. CE-MS Approaches for Glyco(proteo)mic Analysis.;

506 a| Available only to authorized users.;

520 a| Explains foundational principles, technology as well the strategies and techniques used in data analysis for metabolic and proteomic studies. It also provides a global overview of recent developments and advances for improving CE-MS sensitivity and reproducibility. An essential handbook for everyone performing metabolomic and proteomic analysis, the information provided here will assist researchers in tapping into the full potential of this technique to answer biological and clinical questions. Readers will also find: A thorough introduction to the principles of capillary electrophoresis, including its fundamentals, CE separation modes, capillary coatings, and the fundamentals of mass spectrometry In-depth examinations of technological developments in capillary electrophoresis, including sample preparation, online preconcentration, detection sensitivity, and metabolic coverage Comprehensive discussions of metabolomic studies, including their biomedical and clinical applications Recent advances in proteomics, including top-down and bottom-up approaches Perfect for analytical and clinical chemists, Capillary Electrophoresis--Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications will also earn a place in the libraries of biochemists, molecular biologists, and other molecular life scientists.;

538 a| Mode of access: World Wide Web;

650 12 a| Electrophoresis, Capillary=| ^A937456;

650 12 a| Mass Spectrometry=| ^A948241;

650 22 a| Proteomics=| ^A937796;

650 22 a| Metabolomics=| ^A1289118;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Ramautar, Rawi.?| UNAUTHORIZED;

700 1 a| Chen, David D. Y.q| (David Da Yong),d| 1963-?| UNAUTHORIZED;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=3397028&scope=site&custid=s5822723&authtype=ip,shib;

947 a| (OCoLC)1346469999;

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949 a| CLICK ON WEB ADDRESSw| ASISh| JMUSIC60;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6745527-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 7/15/2026x| EBOOKz| JERESOURCE;

Capillary electrophoresis-mass spectrometry for proteomics and metabolomics principles and applications / edited by Rawi Ramautar and David D.Y. Chen.

Other author	Ramautar, Rawi.
Other author	Chen, David D. Y. (David Da Yong), 1963-
Format	Electronic
Publication Info	Weinheim, Germany : Wiley-VCH, [2023]
Description	xiv, 386 pages : color illustrations ; 25 cm
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	Electrophoresis, Capillary Mass Spectrometry Proteomics Metabolomics

Contents	1. Capillary Electrophoresis-Mass Spectrometry Interfacing: Principles and Recent Developments -- 2. Data Analysis Strategies in CE-MS for Metabolomics -- 3. Data Processing Workflow for Relative Quantification from Label-Free and Isobaric Labeling-Based Untargeted Shotgun Proteomics: From Database Search to Differential Expression Analysis -- 4. Data Processing in Metabolomics Capillary Electrophoresis-Mass Spectrometry -- 5. Utility and Advances of Capillary Electrophoresis-Mass Spectrometry for Metabolomics -- 6. Comprehensive Lipid Profiling by Multisegment Injection-Nonaqueous Capillary Electrophoresis-Mass Spectrometry: Expanding Coverage Beyond Hydrophilic Metabolites -- 7. Strategies for Identification of Modified Amino Acids with CE-MS in Metabolomics -- 8. CE-MS Approaches for Single-Cell Metabolomics -- 9. CE-MS Approaches for Peptidomics -- 10. Capillary Zone Electrophoresis-Mass Spectrometry for Top-Down Proteomics: Technological Development and Biological Applications -- 11. CE-MS Methods for the Characterization of Monoclonal Antibodies -- 12. CE and CE-MS Approaches for Glycan Analysis -- 13. CE-MS Approaches for Glyco(proteo)mic Analysis.
Abstract	Explains foundational principles, technology as well the strategies and techniques used in data analysis for metabolic and proteomic studies. It also provides a global overview of recent developments and advances for improving CE-MS sensitivity and reproducibility. An essential handbook for everyone performing metabolomic and proteomic analysis, the information provided here will assist researchers in tapping into the full potential of this technique to answer biological and clinical questions. Readers will also find: A thorough introduction to the principles of capillary electrophoresis, including its fundamentals, CE separation modes, capillary coatings, and the fundamentals of mass spectrometry In-depth examinations of technological developments in capillary electrophoresis, including sample preparation, online preconcentration, detection sensitivity, and metabolic coverage Comprehensive discussions of metabolomic studies, including their biomedical and clinical applications Recent advances in proteomics, including top-down and bottom-up approaches Perfect for analytical and clinical chemists, Capillary Electrophoresis--Mass Spectrometry for Proteomics and Metabolomics: Principles and Applications will also earn a place in the libraries of biochemists, molecular biologists, and other molecular life scientists.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
ISBN	9783527349210 (hardcover)
ISBN	3527349219 (hardcover)
ISBN	(ePDF)
ISBN	(ePub)
ISBN	(oBook)

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Capillary electrophoresis-mass spectrometry for proteomics and metabolomics principles and applications / edited by Rawi Ramautar and David D.Y. Chen.

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