Advanced glycation end-products sources and effects / [edited by Patrik Bast].
| Other author | Bast, Patrik. |
| Format | Electronic |
| Publication Info | New York : Nova Science Publishers, Inc., [2020] |
| Description | 1 online resource |
| Supplemental Content | Full text available from Ebook Central - Academic Complete |
| Subjects |
| Series | Biochemistry and molecular biology in the post genomic era |
| Contents | Advanced glycation end-products and adipose tissue dysfunction / Manu Sudhakar -- Advanced glycation end products and their effects on vascular cell function- modulation by miRNAs / S. Manju Devi and P.R. Sudhakaran -- Glycation, advanced glycation end products and diabetes / Haixia Chen and Yue Chen -- Role of endogenous secretory receptor for advanced glycation end product in diabetes mellitus and its complications / R. Vimalavathini and S.H.R. Subhashri -- Protective role of salinity a gainst the accumulation of advanced glycation end products in embryogenic suspension cultures of dactylis glomerata L. / Eva Popova, Lyuben Zagorchev, Rositsa Tsekovska, Roumyana Mironova and Mariela Odjakova. |
| Abstract | "Advanced Glycation End-Products: Sources and Effects attempts to describe the role of advanced glycation end-products, particularly dietary advanced glycation end-products, in the pathological expansion of adipose tissue as well as their implications in the development of obesity associated complications. The effects of advanced glycation end-products on vasculature and their pathological implications are also described, focusing on the epigenetic mechanisms (particularly that of miRNA) modulating their effects. The authors summarize the information available on the impact of hyperglycemia on the influencing factors of non-enzymatic glycosylation, the formation of advanced glycation end-products, and the role of advanced glycation end-products and their specific receptors in diabetes. The role of advanced glycation end-products to diabetic complications is examined in conjunction with the protective role of the endogenous secretory receptor for advanced glycation end-products (esRAGE) and the therapeutic interventions that would mimic esRAGE activity. In closing, poly-L-lysine modified with advanced glycation end-products is prepared and used as an antigen to generate a single-chain fragment variable monoclonal antibody (scFv mAb) through phage display technology"-- Provided by publisher. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Source of description | Description based on print version record and CIP data provided by publisher; resource not viewed. |
| Issued in other form | Print version: Advanced glycation end-products New York : Nova Science Publishers, Inc., [2020] 9781536175479 |
| Genre/form | Electronic books. |
| LCCN | 2020006787 |
| ISBN | 9781536175554 (adobe pdf) |
| ISBN | (paperback) |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |