Library design, search methods, and applications of fragment-based drug design / Rachelle J. Bienstock, editor ; sponsored by the ACS Division of Chemical Information and ACS Division of Computers in Chemistry.

Other author Bienstock, Rachelle J.
Other author American Chemical Society. Division of Chemical Information.
Other author American Chemical Society. Division of Computers in Chemistry.
Format Electronic
Publication InfoWashington, DC : American Chemical Society,
Descriptionx, 204 p. : ill. (some col.) ; 24 cm.
Supplemental ContentFull text available from ACS eBooks Complete Collection
Subjects
Combinatorial Chemistry Techniques.
Drug Design.
Drug Discovery--methods.
Small Molecule Libraries.

SeriesACS symposium series ; 1076
ACS symposium series ; 1076. 0097-6156 ^A462116
Contents Overview : fragment based drug design -- Designing and searching fragment libraries -- Validation of reaction vectors for de novo design -- Design and application of fragment libraries for protein crystallography -- Ligand-based virtual screening using Bayesian inference network -- A computational fragment approach by mining the protein data bank: library design and bioisosterism -- Computational screening : docking -- A fragment based docking engine : eHiTS -- Fragment-based high-throughput docking and library tailoring -- Leads from fragments : fragment growing and linking -- Fragment-based high-throughput docking and library tailoring -- Fragment-based drug discovery for diseases of the central nervous system.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2011035971
ISBN9780841224926 (alk. paper)

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