Management of dysregulated immune response in the critically ill / Zsolt Molnar, Marlies Ostermann, Manu Shankar-Hari, editors.
| Other author | Molnár, Zsolt, editor. |
| Other author | Ostermann, Marlies, editor. |
| Other author | Shankar-Hari, Manu, editor. |
| Format | Electronic |
| Publication | Cham : Springer, [2023] |
| Copyright Date | ©2023 |
| Description | 1 online resource (xxiii, 311) : illustrations (chiefly color). |
| Supplemental Content | Direct link to eBook |
| Subjects |
| Series | Lessons from the ICU Lessons from the ICU. ^A1456670 |
| Contents | Foreword -- Preface -- Part I. The Host Immune Response -- Phenotypes -- The Dysregulated Host Response -- What is Cytokine Storm? -- Hemophagocytic Lymphohistiocytosis -- Extracorporeal Circulation Related Immune response -- Vasoplegic Shock -- Part II. Assessing Dysregulated Immune Response at the Bedside -- Pro- and anti-inflammatory biomarkers -- How to interpret procalcitonin? -- Assessment of the macro-, and microcirculation -- Part III. Dysregulated Immune Response and organ dysfunction -- Heart and circulation -- Brain -- Kidneys -- Liver -- Hemostasis -- The muscles -- Part IV. Modulating the immune response -- The Role of Steroids -- Why did Anti-Cytokine Therapies Fail in the Past? -- Extracorporeal cytokine removal. |
| Abstract | This book, part of the European Society of Intensive Care Medicine (ESICM) textbook series, deals with dysregulated host response a relatively new term introduced by the Sepsis-3 definitions in 2016. In contrast to systemic inflammatory response syndrome (SIRS) that has been used for nearly 30 years, this is a fundamentally new concept, which requires some sort of a paradigm shift in the way of thinking of critical care physicians. This change obviously requires time and after 5 years, time is ripe to summarize the knowledge in the form of a comprehensive book. The book is split in 4 sections. In the first one, the host immune response is explained in 11 chapters, followed by the next part, summarizing the possible tools for assessment at the bedside. The third and the fourth parts focus on the effects of dysregulated immune response on vital organ function and on the possible ways of immunomodulation. Written by internationally acclaimed experts of the field, the book is of value for all those intensivists and allied professionals working in ICUs. |
| Bibliography note | Includes bibliographical references. |
| Source of description | Print version record. |
| Issued in other form | Print version: MANAGEMENT OF DYSREGULATED IMMUNE RESPONSE IN THE CRITICALLY ILL. [Place of publication not identified] : SPRINGER INTERNATIONAL PU, 2023 3031175719 |
| ISBN | 9783031175725 (electronic bk.) |
| ISBN | 3031175727 (electronic bk.) |
| Standard identifier# | 10.1007/978-3-031-17572-5 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |