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020 a| 9780128198698q| (hardcover);

020 a| 0128198699q| (hardcover);

020 z| 9780128198841 (ePub ebook);

035 a| (WaSeSS)ssj0003145951;

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130 0 a| Principles of clinical pharmacology?| UNAUTHORIZED;

245 10 a| Atkinson's principles of clinical pharmacologyh| [electronic resource] /c| edited by Shiew-Mei Huang, Juan J. L. Lertora, Paolo Vicini, Arthur J. Atkinson Jr.;

246 30 a| Principles of clinical pharmacology;

250 a| Fourth edition.;

260 a| London, United Kingdom :b| Academic Press,c| [2022];

300 a| xxi, 739 pages :b| illustrations (black and white, and color) ;c| 28 cm;

500 a| Preceded by Principles of clinical pharmacology / Arthur J. Atkinson, Jr. ... [et al.]. 3rd ed. 2012.;

504 a| Includes bibliographical references and index.;

505 00 t| Introduction to clinical pharmacology --t| Clinical pharmacokinetics --t| Compartmental analysis of drug distribution --t| Drug absorption and bioavailability --t| Effect of kidney diease on pharmacokinetics --t| Pharmacokinetics in patients requiring renal replacement therapy --t| Effect of liver disease on pharmacokinetics --t| Noncompartmental and compartmental approaches to pharmacokinetic data analysis --t| Population pharmacokinetics --t| Pathways of drug metabolism --t| Bioanalytical methods: technological platforms and method validation --t| Clinical pharmacogenetics --t| Mechanisms and genetics of drug transport --t| Drug-drug interactions --t| Biochemical mechanisms of drug toxicity --t| Pharmacogenomic mechanisms of drug toxicity --t| Biomarkers in drug development --t| Imaging in drug development --t| Dose-effect and concentration-effect analysis --t| Time course of drug response --t| Disease progress models --t| Sex-specific pharmacological differences --t| Drug therapy in pregnant and nursing women --t| Pediatric clinical pharmacology and therapeutics --t| Medication therapy in older adults --t| Clinical analysis of adverse drug reactions and pharmacovigilance --t| Quality assessment of drug therapy --t| Portfolio and project planning and management in drug discovery, evaluation, development, and regulatory process --t| Drug discovery --t| Nonclinical drug development --t| Preclinical prediction of human pharmacokinetics --t| Phase 1 clinical studies --t| Pharmacokinetic and pharmacodynamic considerations in the development of biotechnology products and large molecules --t| Design of clinical development programs --t| The role of the FDA in guiding drug development --t| Emerging clinical pharmacology topics in drug development and precision medicine.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 12 a| Pharmacological Phenomena=| ^A1280158;

650 22 a| Drug Discovery=| ^A1013013;

650 22 a| Clinical Trials as Topic=| ^A920927;

650 22 a| Pharmaceutical Preparationsx| metabolism=| ^A933588;

650 22 a| Pharmacology, Clinical=| ^A921532;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Huang, Shiew-Mei.=| ^A946563;

700 1 a| Lertora, Juan.?| UNAUTHORIZED;

700 1 a| Vicini, Paolo.?| UNAUTHORIZED;

700 1 a| Atkinson, Arthur J.,c| Jr.=| ^A962554;

856 40 z| Full text available from eBook - Pharmacology, Toxicology and Pharmaceutical Science 2021 [EBCPTPS21]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780128198698;

947 a| (OCoLC)1246540123;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

949 a| CLICK ON WEB ADDRESSw| ASISh| HSL77;

949 a| CLICK ON WEB ADDRESSw| ASISh| JMUSIC60;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6705149-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 3/13/2026x| EBOOKz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6705149-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 3/13/2026x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6705149-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 3/13/2026x| EBOOKz| JERESOURCE;

Atkinson's principles of clinical pharmacology / edited by Shiew-Mei Huang, Juan J. L. Lertora, Paolo Vicini, Arthur J. Atkinson Jr.

Format	Electronic
Edition	Fourth edition.
Publication Info	London, United Kingdom : Academic Press, [2022]
Description	xxi, 739 pages : illustrations (black and white, and color) ; 28 cm
Supplemental Content	Full text available from eBook - Pharmacology, Toxicology and Pharmaceutical Science 2021 [EBCPTPS21]
Subjects	Pharmacological Phenomena Drug Discovery Clinical Trials as Topic Pharmaceutical Preparations--metabolism. Pharmacology, Clinical

Other author/creator	Huang, Shiew-Mei.
Other author/creator	Lertora, Juan.
Other author/creator	Vicini, Paolo.
Other author/creator	Atkinson, Arthur J., Jr.
Uniform title	Principles of clinical pharmacology
Portion of title	Principles of clinical pharmacology
Contents	Introduction to clinical pharmacology -- Clinical pharmacokinetics -- Compartmental analysis of drug distribution -- Drug absorption and bioavailability -- Effect of kidney diease on pharmacokinetics -- Pharmacokinetics in patients requiring renal replacement therapy -- Effect of liver disease on pharmacokinetics -- Noncompartmental and compartmental approaches to pharmacokinetic data analysis -- Population pharmacokinetics -- Pathways of drug metabolism -- Bioanalytical methods: technological platforms and method validation -- Clinical pharmacogenetics -- Mechanisms and genetics of drug transport -- Drug-drug interactions -- Biochemical mechanisms of drug toxicity -- Pharmacogenomic mechanisms of drug toxicity -- Biomarkers in drug development -- Imaging in drug development -- Dose-effect and concentration-effect analysis -- Time course of drug response -- Disease progress models -- Sex-specific pharmacological differences -- Drug therapy in pregnant and nursing women -- Pediatric clinical pharmacology and therapeutics -- Medication therapy in older adults -- Clinical analysis of adverse drug reactions and pharmacovigilance -- Quality assessment of drug therapy -- Portfolio and project planning and management in drug discovery, evaluation, development, and regulatory process -- Drug discovery -- Nonclinical drug development -- Preclinical prediction of human pharmacokinetics -- Phase 1 clinical studies -- Pharmacokinetic and pharmacodynamic considerations in the development of biotechnology products and large molecules -- Design of clinical development programs -- The role of the FDA in guiding drug development -- Emerging clinical pharmacology topics in drug development and precision medicine.
General note	Preceded by Principles of clinical pharmacology / Arthur J. Atkinson, Jr. ... [et al.]. 3rd ed. 2012.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
ISBN	9780128198698 (hardcover)
ISBN	0128198699 (hardcover)

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