Pathobiology of Alzheimer's Disease
| Author/creator | Goate, Alison M. Volume Editor |
| Other author | Ashall, Frank Volume Editor |
| Other author | Jenner, Peter Contribution by |
| Format | Electronic |
| Publication Info | Academic Press [Imprint] San Diego : Elsevier Science & Technology Books |
| Description | 256 p. ill 09.000 x 06.000 in. |
| Supplemental Content | Full text available from eBook - Neuroscience 1995 - 2006 |
| Subjects |
| Series | Neuroscience Perspectives Ser. |
| Summary | Annotation <b>Neuroscience Perspectives</b> provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.<br />Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.<br />The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field.<br />With genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease.<br />Although APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research.<br /><br />*<br />* Reviews the current knowledge of the pathogenesis of Alzheimer's Disease from a clinical perspective to a genetic and cell biological perspective<br />* A comprehensive description of the role of amyloid B-protein precursor in Alzheimer's disease.<br />* Up-to-date research data<br />* Clear illustrations complement the text<br /> |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| ISBN | 9780122869655 |
| ISBN | 0122869656 (Trade Cloth) Active Record |
| Standard identifier# | 9780122869655 |
| Stock number | 00991439 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |