Evolutionary cell biology the origins of cellular architecture / Michael Lynch.

Author/creator Lynch, Michael, 1951-
Other author Oxford University Press.
Format Electronic
Publication InfoOxford ; New York, NY : Oxford University Press, 2024
Descriptionxxv, 675 pages : illustrations (chiefly color) ; 25 cm
Supplemental ContentFull text available from Oxford Scholarship Online
Subjects

Contents Introduction. Evolutionary cell biology -- The origin of cells -- The major lines of descent -- The genetic mechanisms of evolution. The population-genetic environment -- Evolution as a population-genetic process -- Evolution of cellular complexity -- Basic cellular features. The cellular environment -- Evolutionary scaling relationships in cell biology -- Cell growth and division -- The cell life cycle -- Cellular senescence -- Structural evolution. The protein world -- Multimerization -- Protein management -- Lipids and membranes -- Cytoskeleton, cell shape, and motility -- Energetics and metabolism. The costs of cellular features -- Resource acquisition and homeostasis -- Enzymes and metabolic pathways -- Information processing. Intracellular errors -- Transcription -- Environmental sensing -- Organismal complexity. Endosymbiosis -- Origins of organismal complexity.
Abstract "The fields of molecular evolution, genome evolution, and evolutionary genetics are now well-established. Remarkably, however, although all evolutionary modifications begin at the cellular level, and despite the advances made in cell biology and microbiology over the past few decades, there is as yet no recognised discipline of evolutionary cell biology. The goal of this book is to help establish the foundations for this emerging field. Its principal aims are twofold: firstly, to promote an understanding among evolutionary biologists as to why the cellular details matter if we are to understand the mechanisms of evolution; secondly, to make clear to non-evolutionary biologists - cell biologists in particular - that evolution is not just a matter of natural selection and optimization, but a process whose reach depends on other population genetic features such as mutation, recombination, and random genetic drift. Although there are many excellent books on cell biology, microbiology, and biophysics, almost no attention is given to evolution. Likewise, although there are numerous evolutionary biology books on the market, none of them gives more than passing attention to details at the cellular level. Thus Evolutionary Cell Biology is genuinely novel, offering a broader understanding of evolutionary processes and an appreciation for the many interesting problems that remain to be solved at the cellular and subcellular levels. This advanced textbook is aimed at both cell biologists and evolutionary biologists. It will be accessible to upper-level undergraduates in biology, and certainly to graduate students in all areas of the life sciences. Professionals from a wide range of fields - cell biology, microbiology, evolution, biophysics, biochemistry, and mathematics - will be exposed to entirely new ideas not traditionally covered in their primary fields of expertise."--Provided by publisher.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2023940185
ISBN0192847287 (hardcover)
ISBN9780192847287 (hardcover)
ISBNebook
ISBN(electronic bk.)

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