RNA therapeutics the evolving landscape of RNA therapeutics / edited by Paloma H. Giangrande, Adjunct Associate Professor or Internal Medicine, University of Iowa, Iwoa City, IA, United States, Vice President of Platform Discovery Sciences, Biology, Wava, Life Science, Cambridge, MA, United States, Dr. Vittorio de Franciscis, Senior Collaborator, National Research Council (CNR), Institute of Genetic and Biomedical Research (IRGB)-UOS, Milan Via Rita Levi Montalcini, Pieve Emanuele (MI), Italy, John J. Rossi, Professor and Chairman, Department of Molecular and Cellular, Biology, Beckman Research Institute of the city of Hope, Monrovia Biomedical Research Center, Monrovia, CA, USA.
| Other author | Giangrande, Paloma H. |
| Other author | Franciscis, Vittorio de. |
| Other author | Rossi, John J. |
| Format | Electronic |
| Publication Info | London : Academic Press, an imprint of Elsevier, [2022] |
| Description | xvi, 456 pages : illustrations ; 24 cm |
| Supplemental Content | Full text available from Elsevier SD eBook - Biochemistry, Genetics and Molecular Biology 2022 |
| Subjects |
| Abstract | Provides a comprehensive overview of RNA therapeutic modalities, from bench-to-bedside, with an emphasis on the increasingly impactful areas of gene therapy, oligonucleotide therapeutics, gene editing and delivery. International leaders in the field examine RNA-based therapeutics tools that have been developed to-date to modulate cellular processes such as transcription, translation and protein function. Approved RNA-based therapies and lessons learned from failed therapies are discussed in-depth, as are evolving advances in RNA biochemical analysis, and similar advances that are enabling clinical application of RNA-based therapies. Later sections discuss delivery technologies, remaining hurdles in research and translation, the therapy development process from the lab to the clinic, and novel RNA-based therapies currently in development. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Issued in other form | ebook version : 9780128217399 |
| Genre/form | Electronic books. |
| LCCN | 2023277227 |
| ISBN | 9780128215951 paperback |
| ISBN | 012821595X paperback |
| ISBN | electronic publication |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |