Translational medicine in CNS drug development / edited by George G. Nomikos, Douglas E. Feltner.
| Other author | Nomikos, George G. (George Goulielmos), 1961- |
| Other author | Feltner, Douglas E. |
| Format | Electronic |
| Publication Info | London, United Kingdom ; San Diego, CA : Academic Press, [2019] |
| Description | xvi, 442 pages : color illustrations ; 29 cm. |
| Supplemental Content | Full text available from eBook - Neuroscience 2019 |
| Supplemental Content | Full text available from eBook - Neuroscience 2007 |
| Supplemental Content | Full text available from eBook - Neuroscience and Psychology 2024 |
| Subjects |
| Series | Handbook of behavioral neuroscience, 1569-7339 ; volume 29 Handbook of behavioral neuroscience ; v. 29. 1569-7339 ^A1053884 |
| Contents | Translating animal models of obesity and diabetes to the clinic / B.M. Geiger and E.N. Pothos -- Giomarker-guided drug development for better defined early patient studies and clinical trial efficiency / Aldemar Degroot -- Modeling and simulation in the translational pharmacology of CNS drugs / Elizabeth C. De Lange and Peter Bonate -- Functional measurements of central nervous system drug effects in early human drug development / Joop van Gerven -- Experimental medicine approaches in CNS drug development / Jeffrey Paul -- New approaches in translational medicine for Phase I clinical trials of CNS drugs / Matthew Macaluso, Michael Krams, Jonathan Savitz, Wayne C. Drevets, and Sheldon H. Preskorn -- Translational approaches for antidepressant drug development / Gerard J. Marek -- Biomarker opportunities to enrich clinical trial populations for drug development in schizophrenia and depression / Bruce J. Kinon -- PET occupancy and competition in translational medicine and CNS drug development / Paul Cumming and Gerhard Gr©ơnder -- Stable isotope labeling kinetics in CNS translational medicine : introduction to SILK technology / Randall J. Bateman ... [et. al.] -- Applications of neurophysiological biomarkers in CNS drug development : focus on psychoses / Yash B. Joshi, Melissa A. Tarasenko, and Gregory A. Light -- Heart rate variability as a translational biomarker for emotional and cognitive deficits / Bart A. Ellenbroek, Meyrick Kidwell, Joyce Colussi-Mas, and Jiun Youn -- Drug discovery in psychiatry : time for human genome-guided solutions / Andreas Papassotiropoulos and Dominique J.-F. de Quervain -- Use of cognition to guide decisions about the safety and efficacy of drugs in early-phase clinical trials / Paul Maruff -- Digital biomarkers in clinical drug development / Amir Kalali, Sarah Richerson, Emilia Ouzunova, Ryan Westphal, and Bradley Miller -- Lessons learned from public private partnerships and consortia : the ADNI paradigm / Enchi Liu -- Regulatory perspectives on the use of biomarkers and personalized medicine in CNS drug development : the FDA viewpoint / Mathangi Gopalakrishnan and Jogarao V.S. Gobburu -- Regulatory considerations for the use of biomarkers and personalized medicine in CNS drug development : a European perspective / Eamon O'Loinsigh and Anjana Bose -- Regulatory science objectives and biomarker qualification through public-private partnerships are critical to delivering innovative treatments for CNS diseases / Diane T. Stephenson and Stephen P. Arneri♯¿ -- The assessment of cognition in translational medicine : a contrast between the approaches used in Alzheimer's disease and major depressive disorder / John E. Harrison and Suzanne Hendrix -- Translational medicine strategies in drug development for neurodevelopmental disorders / Siddharth Srivastava, Mustafa Sahin, and Lisa Prock -- Translational medicine strategies in drug development for mood disorders / Zihang Pan, Radu C. Grovu, and Roger S. McIntyre -- Translational medicine strategies in Alzheimer's disease drug development / Veronika Logovinsky -- Experimental medicine models in generalized anxiety disorder and social anxiety disorder / David S. Baldwin and Ayman Abou-Aisha -- Translational medicine strategies in PTSD drug development / Dan J. Stein, Willie Daniels, and Brian H. Harvey -- Translating neurobiology into practice in tobacco, alcohol, drug, and behavioral addictions / Benjamin Srivastava and Mark S. Gold -- Translational medicine strategies for drug development for impulsive aggression / Emil F. Coccaro, Royce Lee, and Neal G. Simon -- Hypothesizing major depression as a subset of remard deficiency syndrome (RDS) linked to polymorphic reward genes ; considerations for translational medicine approaches for future drug development -- Traveling through the storm : leveraging virtual patient monitoring and artificial intelligence to observe, predict, and affect patient behavior in CNS drug development / Adam Hanina and Laura Shafner. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2021277392 |
| ISBN | 9780128031612 hardcover |
| ISBN | 0128031611 hardcover |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | ✔ Available |