Toxicoepigenetics core principles and applications / edited by Shaun D. McCullough, Dana C. Dolinoy.
| Other author | McCullough, Shaun D. |
| Other author | Dolinoy, Dana C. |
| Format | Electronic |
| Publication Info | London, United Kingdom ; San Diego, CA, United States : Academic Press, an imprint of Elsevier, [2019] |
| Description | xv, 412 pages : illustrations, portraits ; 24 cm |
| Supplemental Content | Full text available from Ebook Central - Academic Complete |
| Supplemental Content | Full text available from eBook - Pharmacology, Toxicology and Pharmaceutical Science 2018 |
| Supplemental Content | Full text available from eBooks on EBSCOhost |
| Subjects |
| Contents | I: Histone modifications and chromatin structure -- Role of histone acetylation and acetyltransferases in gene regulation -- The role of histone methylation and methyltransferases in gene regulation -- Chromatin accessibility as a strategy to detect changes associated with development, disease, and exposure and susceptibility to chemical toxins -- Implications for chromatin biology in toxicology -- II: DNA methylation -- The role of DNA methylation in gene regulation -- Implications of DNA methylation in toxicology -- DNA methylation as a biomarker in environmental epidemiology -- DNA hydroxymethylation: implications for toxicology and epigenetic epidemiology -- III: Noncoding RNAs -- The role of noncoding RNAs in gene regulation -- miRNAs and lncRNAs as biomarkers of toxicant exposure -- IV: Special considerations in toxicoepigenetics research -- Germline and transgenerational impacts of toxicant exposures -- Novel bioinformatics methods for toxicoepigenetics -- Incorporating epigenetics into a risk assessment framework -- V: Protocols for toxicoepigenetics research -- Chromatin immunoprecipitation: an introduction, overview, and protocol -- Methods for analysis of DNA methylation -- Methods for analyzing miRNA expression. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2021301183 |
| ISBN | 9780128124338 paperback |
| ISBN | 0128124334 paperback |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | ✔ Available |