Targeting Cell Survival Pathways to Enhance Response to Chemotherapy.
| Other author | Johnson, Daniel E. Volume Editor |
| Format | Electronic |
| Publication Info | Academic Press [Imprint] Oxford : Elsevier Science & Technology |
| Description | 09.250 x 07.500 in. |
| Supplemental Content | Full text available from eBook - Biomedical Science and Medicine 2018 |
| Series | Cancer Sensitizing Agents for Chemotherapy Ser. Volume 3 |
| Summary | Annotation Targeting Cell Survival Pathways to Enhance Response to Chemotherapy encompasses recently developed molecular targeting agents and approaches that suppress cell survival signaling. Cell survival signaling attenuates the effectiveness of conventional chemotherapy and numerous mechanisms have been described, and continue to be described, which contribute to cell survival in the face of chemotherapy treatment. Key pathways leading to chemoresistance emanate from growth factor receptors, PI3K, STAT3, anti-apoptotic Bcl-2 family members, autophagy, and the DNA damage response pathway. New advances have underscored the potential of targeting each of these cell survival mechanisms to improve responsiveness to chemotherapy. This book reviews these recent advances and provides a foundational background and hints of new opportunities for basic, translational, and clinical investigators focused on improving therapeutic responses to chemotherapy. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| ISBN | 9780128137536 |
| ISBN | 0128137533 (Trade Paper) Publication Cancelled |
| Standard identifier# | 9780128137536 |
| Stock number | C2016-0-05258-0 01167891 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |