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100 1 a| Sharples, Frances Ellen.=| ^A1328492;

245 10 a| Potential risks and benefits of gain-of-function researchh| [electronic resource] :b| summary of a workshop /c| Frances Sharples, Jo Husbands, Anne-Marie Mazza, Audrey Thevenon, and India Hook-Barnard, Rapporteurs, Board on Life Sciences, Division on Earth and Life Studies, Committee on Science, Technology, and Law, Policy and Global Affairs Division, Board on Health Sciences Policy, Institute of Medicine, National Research Council and Institute of Medicine of The National Academies.;

260 a| Washington, D.C. :b| The National Academies Press,c| [2015];

300 a| xiv, 125 pages :b| color illustration ;c| 23 cm;

504 a| Includes bibliographical references (pages 71-76).;

506 a| Available only to authorized users.;

520 a| "On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting."--c| Publisher's description.;

530 a| Also issued online.;

538 a| Mode of access: World Wide Web;

650 7 a| Epidemicsx| Prevention.2| fast0| (OCoLC)fst00914085;

651 7 a| United States.2| fast0| (OCoLC)fst01204155?| UNAUTHORIZED;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Husbands, Joseph Dottin.?| UNAUTHORIZED;

700 1 a| Mazza, Anne-Marie.=| ^A869333;

700 1 a| Thevenon, Audrey.=| ^A1331195;

700 1 a| Hook-Barnard, India.=| ^A1022061;

710 2 a| National Research Council (U.S.).b| Board on Life Sciences.=| ^A535504;

710 2 a| National Research Council (U.S.).b| Committee on Science, Technology, and Law.=| ^A1034277;

710 2 a| Institute of Medicine (U.S.).b| Board on Health Sciences Policy.=| ^A846898;

776 08 a| Potential Risks and Benefits of Gain-of-Function Research (Symposium) (2014 : Washington, D.C.).t| Potential risks and benefits of gain-of-function research.d| Washington, D.C. : National Academies Press, [2015]w| (OCoLC)907932833;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=3439684;

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Potential risks and benefits of gain-of-function research summary of a workshop / Frances Sharples, Jo Husbands, Anne-Marie Mazza, Audrey Thevenon, and India Hook-Barnard, Rapporteurs, Board on Life Sciences, Division on Earth and Life Studies, Committee on Science, Technology, and Law, Policy and Global Affairs Division, Board on Health Sciences Policy, Institute of Medicine, National Research Council and Institute of Medicine of The National Academies.

Author/creator	Sharples, Frances Ellen
Format	Electronic
Publication Info	Washington, D.C. : The National Academies Press, [2015]
Description	xiv, 125 pages : color illustration ; 23 cm
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Epidemics--United States. --Prevention. --Congresses.

Other author/creator	Husbands, Joseph Dottin.
Other author/creator	Mazza, Anne-Marie.
Other author/creator	Thevenon, Audrey.
Other author/creator	Hook-Barnard, India.
Other author/creator	National Research Council (U.S.). Board on Life Sciences.
Other author/creator	National Research Council (U.S.). Committee on Science, Technology, and Law.
Other author/creator	Institute of Medicine (U.S.). Board on Health Sciences Policy.
Abstract	"On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting."-- Publisher's description.
Bibliography note	Includes bibliographical references (pages 71-76).
Access restriction	Available only to authorized users.
Other forms	Also issued online.
Technical details	Mode of access: World Wide Web
Issued in other form	Potential Risks and Benefits of Gain-of-Function Research (Symposium) (2014 : Washington, D.C.). Potential risks and benefits of gain-of-function research. Washington, D.C. : National Academies Press, [2015]
Genre/form	Electronic books.
LCCN	2015452357
ISBN	9780309367837 (pbk.)
ISBN	0309367832

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