Medicinal chemistry fundamentals / Roland Barret.
| Author/creator | Barret, Roland |
| Format | Electronic |
| Publication Info | London, UK : ISTE Press, Elsevier, [2018] |
| Description | xi, 160 pages : illustrations ; 24 cm. |
| Supplemental Content | Full text available from eBook - Chemical Engineering 2018 |
| Subjects |
| Series | Molecular, green, medical and pharmacological chemistry Molecular, green, medicinal, and pharmacological chemistry series. UNAUTHORIZED |
| Contents | Medicines and drugs -- Importance and evaluation of the pKa -- Importance and evaluation of lipophilicity -- Importance and evaluation of solubility -- Importance and evaluation of the polar surface area (PSA and TPSA) -- Lipinski's rule of five -- Principle of a prodrug -- Pharmacophore -- The European pharmacopoeia. |
| Abstract | Medicinal Chemistry: Fundamentals presents the cycle of the life of drugs, their physico-chemical properties, and consequences that arise in development. The fundamental concepts of Medicinal Chemistry (pharmacophore, prodrugs, Lipinsky rules) are also presented, including discussions on specific concerns of the European Pharmacopeia - the industrialist's bible - its role, and a description of the monographs of active principles. |
| Bibliography note | Includes bibliographical references (pages 151-157) and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| ISBN | 9781785482885 hardcover |
| ISBN | 1785482882 hardcover |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |