The dynamic neuron a comprehensive survey of the neurochemical basis of synaptic plasticity / John Smythies.

Author/creator Smythies, John R., 1922-
Format Electronic
Publication InfoCambridge, Mass. : MIT Press,
Descriptionviii, 150 p. : ill. ; 24 cm.
Supplemental ContentFull text available from eBooks on EBSCOhost
Supplemental ContentFull text available from MIT Press Direct to Open Backfile STEAM Monographs D2O
Subjects

Contents Machine generated contents note: Chapter 1 -- Synaptic Biochemistry 1 -- 1.1 Introduction 1 -- 1.2 Evidencefor Synaptic Plasticity 5 -- 1.3 An Introduction to the Glutamate Synapse and Its Redox-Related -- Biochemical Features 6 -- 1.4 Biochemical Factors in Synaptic Plasticity 9 -- 1.5 The Biochemical Basis of the Hebbian Synapse 12 -- 1.6 More Redox Reactions at the Synapse 15 -- Chapter 2 -- Endocytosis and Exocytosis 27 -- 2.1 The Role of Endocytosis 27 -- 2.2 Some Enzymes Involved in Endocytosis 35 -- 2.3 Exocytosis 37 -- 2.4 Ubiquitation 38 -- 2.5 The Special Case of Endocytosis in Neurons 40 -- 2.6 The Functional Significance of Membrane and Receptor -- Endocytosis 41 -- Chapter 3 -- Special Proteins 47 -- 3.1 The Role of Cell Adhesion Molecules 47 -- 3.2 Scaffolding Proteins 55 -- 3.3 Axon Growth-Directing Proteins 60 -- 3.4 Role of Neurotropins 62 -- 3.5 Role of Actin 64 -- 3.6 Role of Local Protein Synthesis 64 -- Chapter 4 -- Miscellaneous Items 67 -- 4.1 Volume Transmission and Spillover 67 -- 4.2 Other Neurotransmitters 69 -- 4.3 Arachidonic Acid Signaling 75 -- 4.4 Hormonal Modulation of Synaptic Plasticity 76 -- 4.5 Psychological Stress 76 -- 4.6 Energy 77 -- 4.7 The Role of Astrocytes 77 -- Chapter 5 -- Pharmacological Implications and Clinical Applications 79 -- 5.1 Pharmacological Implications 79 -- 5.2 Clinical Applications 80 -- Chapter 6 -- Conclusions 91 -- Appendix A -- mRNAs Whose Level Is Altered Following Glutamate Receptor -- Stimulation 93 -- Appendix B -- Receptors That Are Endocytosed 97.
General note"A Bradford book."
Bibliography noteIncludes bibliographical references (p. [107]-143) and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2001058700
ISBN0262194732 (hbk.)

Availability

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