| Contents |
Intro; Preface; Acknowledgments; Contents; 1: Epidemiology and Risk Factors for Esophageal Cancer; Introduction; Epidemiology; Incidence; Esophageal Adenocarcinoma; Esophageal Squamous Cell Carcinoma; Mortality; Survival; Risk Factors; Esophageal Adenocarcinoma; Age and Gender; Ethnicity; Eating Disorders; Obesity; Bulimia Nervosa; Gastroesophageal Reflux Disease; Barrett's Esophagus; Socioeconomic Status; Occupation; Helicobacter pylori Infection; Diet; Hot Food and Beverage; Meat Consumption; Fruit and Vegetables; Minerals and Vitamins; Flavonoids; Vitamin D; N-Nitrosodimethylamine (NDMA) |
| Contents |
FolateDrugs; Sex Steroids; Proton Pump Inhibitors; Bisphosphonates; Nonsteroidal Anti-inflammatory Agents and Aspirin; Statins; Alcohol Consumption and Tobacco Smoking; Metabolic Disorders; Esophageal Squamous Cell Carcinoma; Age and Gender; Ethnicity; Alcohol Consumption and Tobacco Smoking; Socioeconomic Status; Occupation; Opium; Diet; Hot Food and Beverages; Eggs; Meat Consumption; Pickles; Tea and Coffee Consumption; Minerals and Vitamins; Toenail Mineral Concentration; NDMA; Folate; Diet-Related Inflammation; Maté Consumption; Tooth Loss and Oral Hygiene; Oral Cancer; Infectious Disease |
| Contents |
Viral DiseaseHelicobacter pylori Infection; Medications; Bisphosphonates; Conclusions; References; 2: Cellular and Molecular Biology of Esophageal Cancer; Introduction; Histological Differences; Applications of Molecular and Cellular Biology; Establishment of an Infectious Cofactor; Human Papillomavirus; Epstein-Barr Virus; Bacteria; Understanding Genetic Mechanisms; Genetic Profiles; MicroRNAs (miRNAs); Cancer Stem Cells; Prognostic Information; Predication of Progression; Guidelines for Medical Therapies; Prediction of Response to Medical Therapies; Predictors for Targeted Therapy |
| Contents |
Research Sources for Molecular and Cellular Studies in Esophageal CancersTissue Studies; Cancer Cell Lines; Animal Models; References; 3: Pathology of Premalignant and Malignant Disease of the Esophagus; Introduction; Pathology of Adenocarcinoma and Its Precursor Lesions; Precursor Lesions of Esophageal Adenocarcinoma: Barrett's Esophagus and Barrett's Esophagus-Associated Dysplasia; Esophageal Adenocarcinoma; Pathology of Squamous Cell Carcinoma and Its Precursor Lesions; Precursor Lesions of Esophageal Squamous Cell Carcinoma; Esophageal Squamous Cell Carcinoma; Assessment of Specimens |
| Contents |
HER2-Neu TestingMicrosatellite Instability Testing; PD-L1 Testing; References; 4: Barrett's Esophagus: Diagnosis and Management; Introduction; Natural History and Risk Factors; Natural History; Risk Factors for BE and EAC; Risk Factors for BE and Strategies to Identify a Screening Population; Risk Factors for the Progression of BE to EAC; Diagnosing Barrett's Esophagus (BE): Current Criteria and Areas of Controversy; Tissue-Based Diagnostic and Risk Markers; BE Surveillance: Current Clinical Strategies and Features That Affect the Implementation of the Surveillance Program |
| Abstract |
The second edition of this very successful book documents the latest progress in the prevention, diagnosis and treatment of esophageal cancer and includes additional sections covering novel targeted therapeutic approaches, immunotherapy and palliative and nutritional support for patients. Furthermore, the sections covering epidemiology, molecular biology, pathology, staging and radiologic and endoscopic assessments have been thoroughly updated and expanded. The principles of surgical resection, radiation therapy and systemic therapy are reviewed and attention is paid to the multidisciplinary approaches to the management of early stage cervical, thoracic, distal and junctional tumors. Updated information is also provided on the treatment of metastatic and recurrent disease as well as approaches that may impact future care, such as chemoprevention. Esophageal Cancer: Prevention, Diagnosis and Therapy will assist specialists from various disciplines, including surgery, radiation therapy, gastroenterology, medical oncology and palliative medicine, in delivering optimal, up-to-date care to the benefit of patients. |
| General note | The Role of Dysplasia in Risk Stratification in Guiding BE Surveillance and Treatment |
| Bibliography note | Includes bibliographical references. |
| Source of description | Print version record. |
| Issued in other form | Print version: Saba, Nabil F. Esophageal Cancer : Prevention, Diagnosis and Therapy. Cham : Springer, ©2020 9783030298319 |
| ISBN | 9783030298326 (electronic bk.) |
| ISBN | 3030298329 (electronic bk.) |
| Standard identifier# |
10.1007/978-3-030-29832-6 |
| Stock number | com.springer.onix.9783030298326 Springer Nature |
