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245 00 a| Biophysical methods for biotherapeuticsh| [electronic resource] :b| discovery and development applications /c| edited by Dr. Tapan K. Das.;

260 a| Hoboken, New Jersey :b| Wiley,c| [2014];

300 a| 1 online resource.;

504 a| Includes bibliographical references and index.;

505 0 a| Biophysical methods applied in early discovery of a biotherapeutic : case study of an EGFR-IGF1R bispecific adnectin / Michael L. Doyle, James W. Bryson, Virginie Lafont, Zheng Lin, Paul E. Morin, Lumelle A. Schneeweis, Aaron P. Yamniuk, and Joseph Yanchunas Jr -- X-ray crystallography for biotherapeutics / Glen Spraggon -- Solubility and early assessment of stability for protein therapeutics / Sheng-Jiun Wu, Gary L. Gilliland and Yiqing Feng -- Biophysical and structural characterization needed prior to proof of concept / Angela W. Blake-Haskins, Yen-Huei Lin, Zhuchun Wu, Melissa D. Perkins, Thomas M. Spitznagel -- Nucleation, aggregation, and conformational distortion / Christopher J. Roberts -- Utilization of chemical labeling and mass spectrometry for the biophysical characterization of biopharmaceuticals / Justin B. Sperry and Lisa M. Jones -- Application of biophysical and high throughput methods in the preformulation of therapeutic proteins? : facts and fictions / Ahmad M. Abdul-Fattah and Hanns-Christian Mahler -- Bioanalytical methods and immunogenicity assays / Bonita Rup, Corinna Krinos-Fiorotti, Boris Gorovits, Hendrik Neubert -- Structures and dynamics of proteins probed by UV resonance raman spectroscopy / Brian S. Leigh, Diana E. Schlamadinger, and Judy E. Kim -- Freezing and drying-induced micro-/nanoheterogeneity in biological solutions / Alptekin Aksan, Vishard Ragoonanan, and Carol Hirschmugl -- Late stage product characterization : applications in formulation, process and manufacturing development / Christine P. Chan and Li Shi -- Biophysical analyses suitable for chemistry, manufacturing and control sections of the biological license application (BLA) / Zahra Shahrokh, Nazila Salamat-Miller, John J. Thomas.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

588 a| Description based on print version record and CIP data provided by publisher.;

650 12 a| Biopharmaceuticsx| methods.=| ^A1202054;

650 22 a| Drug Discoveryx| methods.=| ^A1023263;

650 22 a| Technology, Pharmaceuticalx| methods.=| ^A931864;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Das, Tapan K.?| UNAUTHORIZED;

776 08 i| Print version:t| Biophysical methods for biotherapeuticsd| Hoboken, New Jersey : Wiley, [2014]z| 9780470938430w| (DLC) 2013038071;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=1642416;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5588528-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 4/16/2021x| EBOOKz| JERESOURCE;

Biophysical methods for biotherapeutics discovery and development applications / edited by Dr. Tapan K. Das.

Other author	Das, Tapan K.
Format	Electronic
Publication Info	Hoboken, New Jersey : Wiley, [2014]
Description	1 online resource.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Biopharmaceutics--methods. Drug Discovery--methods. Technology, Pharmaceutical--methods.

Contents	Biophysical methods applied in early discovery of a biotherapeutic : case study of an EGFR-IGF1R bispecific adnectin / Michael L. Doyle, James W. Bryson, Virginie Lafont, Zheng Lin, Paul E. Morin, Lumelle A. Schneeweis, Aaron P. Yamniuk, and Joseph Yanchunas Jr -- X-ray crystallography for biotherapeutics / Glen Spraggon -- Solubility and early assessment of stability for protein therapeutics / Sheng-Jiun Wu, Gary L. Gilliland and Yiqing Feng -- Biophysical and structural characterization needed prior to proof of concept / Angela W. Blake-Haskins, Yen-Huei Lin, Zhuchun Wu, Melissa D. Perkins, Thomas M. Spitznagel -- Nucleation, aggregation, and conformational distortion / Christopher J. Roberts -- Utilization of chemical labeling and mass spectrometry for the biophysical characterization of biopharmaceuticals / Justin B. Sperry and Lisa M. Jones -- Application of biophysical and high throughput methods in the preformulation of therapeutic proteins? : facts and fictions / Ahmad M. Abdul-Fattah and Hanns-Christian Mahler -- Bioanalytical methods and immunogenicity assays / Bonita Rup, Corinna Krinos-Fiorotti, Boris Gorovits, Hendrik Neubert -- Structures and dynamics of proteins probed by UV resonance raman spectroscopy / Brian S. Leigh, Diana E. Schlamadinger, and Judy E. Kim -- Freezing and drying-induced micro-/nanoheterogeneity in biological solutions / Alptekin Aksan, Vishard Ragoonanan, and Carol Hirschmugl -- Late stage product characterization : applications in formulation, process and manufacturing development / Christine P. Chan and Li Shi -- Biophysical analyses suitable for chemistry, manufacturing and control sections of the biological license application (BLA) / Zahra Shahrokh, Nazila Salamat-Miller, John J. Thomas.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Source of description	Description based on print version record and CIP data provided by publisher.
Issued in other form	Print version: Biophysical methods for biotherapeutics Hoboken, New Jersey : Wiley, [2014] 9780470938430
Genre/form	Electronic books.
LCCN	2013038702
ISBN	9781118354674 (pdf)
ISBN	9781118354681 (epub)
ISBN	9781118354667 ( mobi)

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Biophysical methods for biotherapeutics discovery and development applications / edited by Dr. Tapan K. Das.

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