Protein NMR spectroscopy practical techniques and applications / edited by Lu-Yun Lian, Gordon Roberts.

Other author Lian, Lu-Yun.
Other author Roberts, G. C. K. (Gordon Carl Kenmure)
Format Electronic
Publication InfoChichester, West Sussex : Wiley,
Descriptionxiv, 351 p., [10] p. of col. plates : ill. ; 26 cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

Contents Sample preparation, data collection and processing / Frederick W. Muskett -- Isotope labelling / Mitsuhiro Takeda and Masatsune Kainosho -- Resonance assignments / Lu-Yun Lian and Igor L. Barsukov -- Measurement of structural restraints / Geerten W. Vuister ... [et al.] -- Calculation of structures from NMR restraints / Peter Guntert -- Paramagnetic tools in protein NMR / Peter H.J. Keizers and Marcellus Ubbink -- Structural and dynamic information on ligand binding / Gordon Roberts -- Macromolecular complexes / Paul C. Driscoll -- Studying partially folded and intrinsically disordered proteins using NMR residual dipolar couplings / Malene Ringkjøbing Jensen ... [et al.].
Abstract "Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful technique in structural biology for obtaining high resolution 3-D structures of proteins, second only, and complementary to X-ray crystallography. Molecules are studied in solution, where conditions are closer to what is found in the cell. It is the primary technique used to obtain information on intrinsically disordered (unfolded) proteins, since these proteins will not crystallize easily.The aim of this book is to provide the newcomer to NMR techniques with practical guidance on how to choose the right experiment, how to carry out the experiment, and how to analyse the resulting spectra. Those who are familiar with the chemical applications of NMR will also find it helpful in describing the special requirements of proteins"-- Provided by publisher.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2011010948
ISBN9780470721933
ISBN0470721936

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