| Contents |
Neurodegenerative diseases : evolving unifying principles / Jeffrey Cummings and Jagan Pillai -- Neurodegenerative diseases as protein misfolding disorders / Tomohiro Nakamura and Stuart A. Lipton -- Calcium hypothesis on neurodegeneration : the case of AD and HD / Daniel A. Ryskamp, Elena Popugaeva, and Ilya Bezprozvanny -- Inflammation in neurodegenerative diseases / Bruce Lamb -- Prion paradigm of human neurodegenerative diseases caused by protein misfolding / Jiri Safar -- Neuropsychiatric features across neurodegenerative diseases / Claudia R. Padilla, Mario F. Mendez -- Brain circuits : pathway for NDD / William Seeley -- Fluid biomarkers indicative of neurodegenerative diseases / Henrik Zetterberg and Jonathan M. Schott -- Predementia disorders : neurodegenerative diseases predecessor states as unifying clinical features / Jagan Pillai -- Genetics of neurodegenerative diseases : sporadic and autosomal dominant forms / Lars Bertram and Max Planck -- An epigenetics perspective on diseases of the central nervous system / Diego Mastroeni -- Mitochondrial changes and bioenergetics in neurodegenerative diseases / Andrew B. Knot and Ella Bossy-Wetzel -- Systems biology in neurodegenerative diseases / Lawrence Rajendran -- Cell culture and iPS cells and neurodegenerative diseases / Roxana Nat -- Animal models of neurodegenerative diseases / David Baglietto-Vargas, Ager RR, Medeiros R, and Frank M. LaFerla -- Metal-protein attenuating compounds in neurodegenerative diseases / Peng Lei, Scott Ayton, and Ashley I. Bush -- Disease modifying therapies in neurodegenerative disorders / Janelle Drouin-Ouellet and Roger A. Barker -- Immunotherapy for neurodegenerative disorders / David Morgan -- Clinical trials and drug development in neurodegenerative diseases : unifying principles / Jeffrey Cummings and Kate Zhong -- Conclusions on neurodegenerative disorders : unifying principles / Jagan Pillai and Jeffrey Cummings. |
