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035 a| (Sirsi) o1164146310;

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049 a| EREE;

100 1 a| Davis, Suja P.,e| author.?| UNAUTHORIZED;

245 10 a| Fatigue and associated factors in adults with inflammatory bowel disease /c| by Suja P. Davis.;

264 1 a| [Greenville, N.C.] :b| [East Carolina University],c| 2020.;

300 a| 172 pages :b| illustrations (some color).;

336 a| textb| txt2| rdacontent;

337 a| computerb| c2| rdamedia;

338 a| online resourceb| cr2| rdacarrier;

347 a| text fileb| PDFc| 2.071 MB2| rda;

490 1 a| ECU College of Nursing dissertation;

538 a| System requirements: Adobe Reader.;

538 a| Mode of access: World Wide Web.;

502 b| Nursingc| East Carolina Universityd| 2020.;

500 a| Presented to the faculty of the Department of College of Nursing.;

500 a| Advisor: Patricia Crane;

500 a| Title from PDF t.p. (viewed March 24, 2021).;

520 3 a| Inflammatory bowel disease (IBD) is an autoimmune disorder of the gastrointestinal tract and is characterized by chronic inflammation. Ulcerative colitis (UC) and Crohn's disease (CD) are the two major forms of IBD. Fatigue is one of the most common symptoms reported by those with IBD and about 22% to 77% of adults with IBD experience fatigue. The purposes of this study were to develop a parsimonious model that describes the influencing factors of fatigue in adults with IBD, adults with CD and adults with UC. The study was a secondary analysis of cross sectional data obtained from IBD partners. The conceptual framework of the study was adapted from the middle range theory of unpleasant symptoms. The variables were organized as physiological, psychological and situational factors as influencing factors with fatigue as the symptom in the framework. The Patient Reported Outcomes Measurement Information System (PROMIS) short-form scales were used to measure fatigue, sleep disturbances, pain interference, anxiety, depression, and satisfaction with social roles (SSR). Additionally, physical activity, demographic and clinical variables were measured. The vast majority of the participants were White (92%) females (72%). The majority of the participants (85%) wre [less-than] 60 years of age. Majority of the participants (63%) had CD in this cohort. Three models were tested based on the conceptual framework to identify the direct and indirect effects of situational, physiological, and psychological factors on IBD-Fatigue. The data best fit with model with situational factors (physical activity and SSR) as the mediators for all adults with IBD, as well as in the stratified evaluation of adults with CD and UC. Significant direct effects were noted from disease activity, age, sleep disturbances, pain interference, anxiety and depression to fatigue in all adults with IBD as well as in adults with CD and UC (p [less-than]. 001). An additional direct effect was noted from narcotics to fatigue in adults with UC (p [less-than]. 001). Indirect effects were noted consistently from sleep disturbances, pain interference, and depression via physical activity and SSR in all final models in adults with IBD, adults with CD and adults with UC (p [less-than]. 001).;

504 a| Includes bibliographical references.;

650 2 a| Inflammatory Bowel Diseases.=| ^A926477;

650 2 a| Fatigue.=| ^A918322;

650 2 a| Adult.=| ^A919078;

700 1 a| Crane, Patricia B.,e| degree supervisor.?| UNAUTHORIZED;

710 2 a| East Carolina University.b| College of Nursing.=| ^A1134029;

830 0 a| ECU College of Nursing dissertation.?| UNAUTHORIZED;

856 40 z| Access via ScholarShipu| http://hdl.handle.net/10342/8619;

949 o| wjh;

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596 a| 1 4;

998 a| 5336234;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5336234-1001l| JNETm| JOYNERr| Ys| Yt| JNE3ETDu| 7/9/2020x| ETDz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5336234-2001l| HSLELECm| HSLr| Ys| Yt| HEETDu| 7/9/2020x| ETDz| HERESOURCE;

Fatigue and associated factors in adults with inflammatory bowel disease / by Suja P. Davis.

Author/creator	Davis, Suja P. author.
Other author	Crane, Patricia B., degree supervisor.
Other author	East Carolina University. College of Nursing.
Format	Theses and dissertations
Publication	[Greenville, N.C.] : [East Carolina University], 2020.
Description	172 pages : illustrations (some color).
Supplemental Content	Access via ScholarShip
Subjects	Inflammatory Bowel Diseases. Fatigue. Adult.

Series	ECU College of Nursing dissertation ECU College of Nursing dissertation. UNAUTHORIZED
Summary	Inflammatory bowel disease (IBD) is an autoimmune disorder of the gastrointestinal tract and is characterized by chronic inflammation. Ulcerative colitis (UC) and Crohn's disease (CD) are the two major forms of IBD. Fatigue is one of the most common symptoms reported by those with IBD and about 22% to 77% of adults with IBD experience fatigue. The purposes of this study were to develop a parsimonious model that describes the influencing factors of fatigue in adults with IBD, adults with CD and adults with UC. The study was a secondary analysis of cross sectional data obtained from IBD partners. The conceptual framework of the study was adapted from the middle range theory of unpleasant symptoms. The variables were organized as physiological, psychological and situational factors as influencing factors with fatigue as the symptom in the framework. The Patient Reported Outcomes Measurement Information System (PROMIS) short-form scales were used to measure fatigue, sleep disturbances, pain interference, anxiety, depression, and satisfaction with social roles (SSR). Additionally, physical activity, demographic and clinical variables were measured. The vast majority of the participants were White (92%) females (72%). The majority of the participants (85%) wre [less-than] 60 years of age. Majority of the participants (63%) had CD in this cohort. Three models were tested based on the conceptual framework to identify the direct and indirect effects of situational, physiological, and psychological factors on IBD-Fatigue. The data best fit with model with situational factors (physical activity and SSR) as the mediators for all adults with IBD, as well as in the stratified evaluation of adults with CD and UC. Significant direct effects were noted from disease activity, age, sleep disturbances, pain interference, anxiety and depression to fatigue in all adults with IBD as well as in adults with CD and UC (p [less-than]. 001). An additional direct effect was noted from narcotics to fatigue in adults with UC (p [less-than]. 001). Indirect effects were noted consistently from sleep disturbances, pain interference, and depression via physical activity and SSR in all final models in adults with IBD, adults with CD and adults with UC (p [less-than]. 001).
General note	Presented to the faculty of the Department of College of Nursing.
General note	Advisor: Patricia Crane
General note	Title from PDF t.p. (viewed March 24, 2021).
Dissertation note	Nursing East Carolina University 2020.
Bibliography note	Includes bibliographical references.
Technical details	System requirements: Adobe Reader.
Technical details	Mode of access: World Wide Web.

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Fatigue and associated factors in adults with inflammatory bowel disease / by Suja P. Davis.

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