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Chromatin regulation and dynamics / edited by Anita Göndör, Department of Microbiology, Tumor and Cell, Biology, Karolinska Institutet, Stockholm, Sweden.
| Other author | Göndör, Anita. |
| Format | Electronic |
| Publication Info | Amsterdam ; Boston : Elsevier, AP, Academic Press is an imprint of Elsevier, [2017] |
| Description | xxii, 473 pages : color illustrations ; 25 cm. |
| Supplemental Content | Full text available from eBook - Biochemistry, Genetics and Molecular Biology 2016 [EBCBGMB16] |
| Subjects |
| Series | Translational epigenetics series Translational epigenetics series. ^A1311478 |
| Contents | A brief introduction to chromatin regulation and dynamics -- Histone modifications and histone variants in pluripotency and differentiation -- Dynamics and function of DNA methylation during development -- ATP-dependent chromatin remodeling : from development to disease -- Chromatin dynamics during the cell cycle -- Epigenetic regulation of replication and replication timing -- Regulation of cellular identity by polycomb and trithorax proteins -- Interplay between chromatin and splicing -- Crosstalk between non-coding RNAs and the epigenome in development -- Epigenetic regulation of nucleolar functions -- Chromatin dynamics and DNA repair -- Regulation of centromeric chromatin -- Telomere maintenance in the dynamic nuclear architecture -- Epigenetic regulation of X-chromosome inactivation -- Interaction between cellular metabolic states and chromatin dynamics -- Circadian plasticity of chromatin states -- 3D nuclear architecture and epigenetic memories : regulators of phenotypic plasticity in development, aging, and cancer. |
| Abstract | "Chromatin regulation and dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, and then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The book also covers the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin regulation and dynamics, as part of the Translational epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, as well as ageing and complex diseases by focusing on recent findings of the fast-moving field of chromatin regulation."-- Provided by publisher. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2017288353 |
| ISBN | 9780128033951 (hbk) |
| ISBN | 0128033959 (hbk) |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |