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245 00 a| Boron nitride nanotubes in nanomedicineh| [electronic resource] /c| edited by Gianni Ciofani, Virgilio Mattoli.;

260 a| Amsterdam ;a| Boston :b| Elsevier/WA, William Andrew is an imprint of Elsevier,c| [2016];

300 a| xvii, 228 pages :b| illustrations, portraits. ;c| 25 cm.;

490 1 a| Micro & nano technologies series;

504 a| Includes bibliographical references and index.;

505 00 a| Machine generated contents note:g| ch. 1t| Introduction to Boron Nitride Nanotubes: Synthesis, Properties, Functionalization, and Cutting /r| Yoke Khin Yap --g| 1.1.t| Introduction --g| 1.2.t| Properties of BNNTs for Potential Biomedical Applications --g| 1.3.t| Synthesis of BNNTs --g| 1.3.1.t| Chemical Vapor Deposition --g| 1.3.2.t| Ball Milling --g| 1.3.3.t| Laser-Based Techniques --g| 1.3.4.t| Large-Scale Synthesis by Plasma-Based Techniques --g| 1.4.t| Comparison of Production Rate, Purity, and Dispersibility of BNNTs --g| 1.5.t| Functionalization and Cutting of BNNTs for Biomedical Applications --g| 1.5.1.t| Noncovalent Functionalization --g| 1.5.2.t| Covalent Functionalization --g| 1.6.t| Summary --t| Acknowledgments --t| References --g| ch. 2t| Functionalization of Boron Nitride Nanotubes for Applications in Nanobiomedicine /r| Takeshi Serizawa --g| 2.1.t| Introduction --g| 2.2.t| Covalent Functionalization --g| 2.2.1.t| Nitrogen Site Reaction --g| 2.2.2.;

505 00 t| Boron Site Reaction --g| 2.3.t| Noncovalent Functionalization --g| 2.3.1.t| Small Molecules with Aromatic Groups --g| 2.3.2.t| Small Molecules without Aromatic Groups --g| 2.3.3.t| Amino Acids --g| 2.3.4.t| Surfactants --g| 2.3.5.t| Peptides --g| 2.3.6.t| Deoxyribonucleic Acids (DNA) --g| 2.3.7.t| Lipids --g| 2.3.8.t| Polysaccharides --g| 2.3.9.t| Polymers --g| 2.4.t| Defect Reaction Approach --g| 2.5.t| Filling BNNTs Approach --g| 2.6.t| Conclusions and Perspectives --t| References --g| ch. 3t| Biocompatibility Evaluation of Boron Nitride Nanotubes /r| Mustafa Culha --g| 3.1.t| Introduction --g| 3.2.t| Common Methods for Evaluating in Vitro Biocompatibility --g| 3.2.1.t| Viability and Cytotoxicity Assays --g| 3.2.2.t| ROS Detection --g| 3.2.3.t| Apoptosis and Necrosis Detection --g| 3.2.4.t| Genotoxicity Assessment --g| 3.3.t| In Vitro Biocompatibility Assessment --g| 3.4.t| In Vivo Biocompatibility Assessment --g| 3.5.t| Future Studies and Perspectives --g| 3.6.t| Conclusions;

505 00 t| Interactions Between BNNTs and Drug Molecules --g| 5.4.1.t| Weak Interactions --g| 5.4.2.t| Covalent Interactions --g| 5.5.t| Integration of Multifunctional Properties in BNNT-Based Drug Carriers --g| 5.5.1.t| Targeting Release --g| 5.5.2.t| Imaging --g| 5.5.3.t| Acting as B Carrier for Boron Neutron Capture Therapy --g| 5.6.t| Biocompatibility, Distribution, and Excretion of BNNTs as Drug Carriers --g| 5.7.t| Future of BNNTs as Drug Carriers --t| References --g| ch. 6t| Applications and Perspectives of Boron Nitride Nanotubes in Cancer Therapy /r| Edesia M.B. de Sousa --g| 6.1.t| Cancer: Aspects of Diagnosis and Treatment --g| 6.2.t| Boron Nitride Nanotubes and Nanomedicine --g| 6.3.t| Drug Delivery --g| 6.4.t| Active Targeting and Uptake --g| 6.5.t| Gene Transfection --g| 6.6.t| Magnetohyperthermia --g| 6.7.t| Boron Neutron Capture Therapy --g| 6.8.t| Perspectives --t| References --g| ch. 7t| Boron Nitride Nanotubes as Magnetic Resonance Imaging Contrast Agents /;

505 00 r| Claudia Forte --g| 7.1.t| Nanomaterials: The Way to Higher Magnetic Resonance Contrast --g| 7.2.t| Superparamagnetic BNNTs as T2-Weighted Contrast Agents --g| 7.3.t| Gd-Doped BNNTs: Promising Contrast Properties at High and Low Fields --g| 7.4.t| Conclusions and Perspectives --g| 7.5.t| Appendix. MRI Contrast Enhancement: The Basics --t| References --g| ch. 8t| Boron Nitride Nanotubes as Nanotransducers /r| Serena Danti --g| 8.1.t| Introduction --g| 8.2.t| BNNT Nanotransducers --g| 8.2.1.t| Piezoelectric Nanotransducers --g| 8.2.2.t| BNNTs as Piezoelectric Transducers --g| 8.2.3.t| BCN-NT Nanotransducers --g| 8.3.t| BNNT Bionanotransducers --g| 8.3.1.t| Ultrasound -- BNNT Systems for Cell Stimulation --g| 8.3.2.t| BNNT Nanotransducers for the Nervous System --g| 8.3.3.t| BNNT Nanotransducers for Muscle --g| 8.3.4.t| BNNT Nanotransducers for Bone --g| 8.4.t| Conclusions and Future Perspectives --t| Acknowledgement --t| References --g| ch. 9;

505 00 t| Optical Properties of Boron Nitride Nanotubes: Potential Exploitation in Nanomedicine /r| Mauro Gemmi --g| 9.1.t| Introduction --g| 9.2.t| Optical Properties of Boron Nitride Nanotubes --g| 9.3.t| Boron Nitride Nanotubes in Nanomedicine --g| 9.4.t| BNNT Nonlinear Optical Properties: Exploitation in Nanomedicine --g| 9.5.t| Conclusions --t| References --g| ch. 10t| Boron Nitride Nanotubes as Bionanosensors /r| Sondipon Adhikari --g| 10.1.t| Introduction --g| 10.2.t| Vibration Analysis of BNNTs with Attached Mass --g| 10.2.1.t| Cantilevered BNNT with a Mass at the Tip --g| 10.2.2.t| Bridged BNNT with a Mass at the Midpoint --g| 10.3.t| Mass Detection and Sensitivity Calculation --g| 10.4.t| Vibrational Analysis of BNNTs Using Molecular Mechanics --g| 10.5.t| Results and Discussions --g| 10.6.t| Conclusions --t| References --g| ch. 11t| Boron Nitride Nanotube Films: Preparation, Properties, and Implications for Biology Applications /r| Ying Chen --g| 11.1.t| Introduction --g| 11.2.;

505 00 t| Growth of BNNT Films --g| 11.2.1.t| Boron Ink Method --g| 11.2.2.t| Vapor Deposition Method --g| 11.3.t| Wettability Properties of BNNT Films --g| 11.4.t| Wettability Modification of BNNT Films --g| 11.5.t| Biocompatibility of BNNT Films --g| 11.6.t| Conclusion --t| References --g| ch. 12t| Structural and Physical Properties of Boron Nitride Nanotubes and Their Applications in Nanocomposites /r| Changhong Ke --g| 12.1.t| Introduction --g| 12.2.t| Structure and Synthesis of BNNTs --g| 12.2.1.t| Structure of BNNTs --g| 12.2.2.t| Synthesis of BNNTs --g| 12.3.t| Physical Properties of BNNTs --g| 12.3.1.t| Mechanical Properties --g| 12.3.2.t| Electrical Properties --g| 12.3.3.t| Thermal Properties --g| 12.4.t| BNNT-Based Nanocomposites --g| 12.5.t| Conclusions and Outlook --t| Acknowledgments --t| References --g| ch. 13t| Boron Nitride Nanotubes in Nanomedicine: Historical and Future Perspectives /r| Gianni Ciofani --g| 13.1.;

505 00 t| Brief History of Boron Nitride Nanotubes: From the Theoretical Hypothesis to the Market --g| 13.2.t| Main Research Groups Involved in BNNT Research --g| 13.3.t| BNNT Availability on the Market --g| 13.4.t| Patent Analysis and Economical Implications --g| 13.5.t| Toward the Future: Regulatory Aspects and Translational Research.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Nanotubes.=| ^A567715;

650 12 a| Nanotubes.=| ^A1349854;

650 12 a| Boron Compounds.=| ^A1484875;

650 7 a| Nanotubes.2| fast0| (OCoLC)fst01032640;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Ciofani, Gianni.?| UNAUTHORIZED;

700 1 a| Mattoli, Virgilio.?| UNAUTHORIZED;

830 0 a| Micro & nano technologies.=| ^A1060517;

856 40 z| Full text available from eBook - Materials Science 2016 [EBCMS16]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780323389457;

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Boron nitride nanotubes in nanomedicine / edited by Gianni Ciofani, Virgilio Mattoli.

Other author	Ciofani, Gianni.
Other author	Mattoli, Virgilio.
Format	Electronic
Publication Info	Amsterdam ; Boston : Elsevier/WA, William Andrew is an imprint of Elsevier, [2016]
Description	xvii, 228 pages : illustrations, portraits. ; 25 cm.
Supplemental Content	Full text available from eBook - Materials Science 2016 [EBCMS16]
Subjects	Nanotubes. Nanotubes. Boron Compounds.

Series	Micro & nano technologies series Micro & nano technologies. ^A1060517
Contents	Machine generated contents note: ch. 1 Introduction to Boron Nitride Nanotubes: Synthesis, Properties, Functionalization, and Cutting / Yoke Khin Yap -- 1.1. Introduction -- 1.2. Properties of BNNTs for Potential Biomedical Applications -- 1.3. Synthesis of BNNTs -- 1.3.1. Chemical Vapor Deposition -- 1.3.2. Ball Milling -- 1.3.3. Laser-Based Techniques -- 1.3.4. Large-Scale Synthesis by Plasma-Based Techniques -- 1.4. Comparison of Production Rate, Purity, and Dispersibility of BNNTs -- 1.5. Functionalization and Cutting of BNNTs for Biomedical Applications -- 1.5.1. Noncovalent Functionalization -- 1.5.2. Covalent Functionalization -- 1.6. Summary -- Acknowledgments -- References -- ch. 2 Functionalization of Boron Nitride Nanotubes for Applications in Nanobiomedicine / Takeshi Serizawa -- 2.1. Introduction -- 2.2. Covalent Functionalization -- 2.2.1. Nitrogen Site Reaction -- 2.2.2.
Contents	Boron Site Reaction -- 2.3. Noncovalent Functionalization -- 2.3.1. Small Molecules with Aromatic Groups -- 2.3.2. Small Molecules without Aromatic Groups -- 2.3.3. Amino Acids -- 2.3.4. Surfactants -- 2.3.5. Peptides -- 2.3.6. Deoxyribonucleic Acids (DNA) -- 2.3.7. Lipids -- 2.3.8. Polysaccharides -- 2.3.9. Polymers -- 2.4. Defect Reaction Approach -- 2.5. Filling BNNTs Approach -- 2.6. Conclusions and Perspectives -- References -- ch. 3 Biocompatibility Evaluation of Boron Nitride Nanotubes / Mustafa Culha -- 3.1. Introduction -- 3.2. Common Methods for Evaluating in Vitro Biocompatibility -- 3.2.1. Viability and Cytotoxicity Assays -- 3.2.2. ROS Detection -- 3.2.3. Apoptosis and Necrosis Detection -- 3.2.4. Genotoxicity Assessment -- 3.3. In Vitro Biocompatibility Assessment -- 3.4. In Vivo Biocompatibility Assessment -- 3.5. Future Studies and Perspectives -- 3.6. Conclusions
Contents	Interactions Between BNNTs and Drug Molecules -- 5.4.1. Weak Interactions -- 5.4.2. Covalent Interactions -- 5.5. Integration of Multifunctional Properties in BNNT-Based Drug Carriers -- 5.5.1. Targeting Release -- 5.5.2. Imaging -- 5.5.3. Acting as B Carrier for Boron Neutron Capture Therapy -- 5.6. Biocompatibility, Distribution, and Excretion of BNNTs as Drug Carriers -- 5.7. Future of BNNTs as Drug Carriers -- References -- ch. 6 Applications and Perspectives of Boron Nitride Nanotubes in Cancer Therapy / Edesia M.B. de Sousa -- 6.1. Cancer: Aspects of Diagnosis and Treatment -- 6.2. Boron Nitride Nanotubes and Nanomedicine -- 6.3. Drug Delivery -- 6.4. Active Targeting and Uptake -- 6.5. Gene Transfection -- 6.6. Magnetohyperthermia -- 6.7. Boron Neutron Capture Therapy -- 6.8. Perspectives -- References -- ch. 7 Boron Nitride Nanotubes as Magnetic Resonance Imaging Contrast Agents /
Contents	Claudia Forte -- 7.1. Nanomaterials: The Way to Higher Magnetic Resonance Contrast -- 7.2. Superparamagnetic BNNTs as T2-Weighted Contrast Agents -- 7.3. Gd-Doped BNNTs: Promising Contrast Properties at High and Low Fields -- 7.4. Conclusions and Perspectives -- 7.5. Appendix. MRI Contrast Enhancement: The Basics -- References -- ch. 8 Boron Nitride Nanotubes as Nanotransducers / Serena Danti -- 8.1. Introduction -- 8.2. BNNT Nanotransducers -- 8.2.1. Piezoelectric Nanotransducers -- 8.2.2. BNNTs as Piezoelectric Transducers -- 8.2.3. BCN-NT Nanotransducers -- 8.3. BNNT Bionanotransducers -- 8.3.1. Ultrasound -- BNNT Systems for Cell Stimulation -- 8.3.2. BNNT Nanotransducers for the Nervous System -- 8.3.3. BNNT Nanotransducers for Muscle -- 8.3.4. BNNT Nanotransducers for Bone -- 8.4. Conclusions and Future Perspectives -- Acknowledgement -- References -- ch. 9
Contents	Optical Properties of Boron Nitride Nanotubes: Potential Exploitation in Nanomedicine / Mauro Gemmi -- 9.1. Introduction -- 9.2. Optical Properties of Boron Nitride Nanotubes -- 9.3. Boron Nitride Nanotubes in Nanomedicine -- 9.4. BNNT Nonlinear Optical Properties: Exploitation in Nanomedicine -- 9.5. Conclusions -- References -- ch. 10 Boron Nitride Nanotubes as Bionanosensors / Sondipon Adhikari -- 10.1. Introduction -- 10.2. Vibration Analysis of BNNTs with Attached Mass -- 10.2.1. Cantilevered BNNT with a Mass at the Tip -- 10.2.2. Bridged BNNT with a Mass at the Midpoint -- 10.3. Mass Detection and Sensitivity Calculation -- 10.4. Vibrational Analysis of BNNTs Using Molecular Mechanics -- 10.5. Results and Discussions -- 10.6. Conclusions -- References -- ch. 11 Boron Nitride Nanotube Films: Preparation, Properties, and Implications for Biology Applications / Ying Chen -- 11.1. Introduction -- 11.2.
Contents	Growth of BNNT Films -- 11.2.1. Boron Ink Method -- 11.2.2. Vapor Deposition Method -- 11.3. Wettability Properties of BNNT Films -- 11.4. Wettability Modification of BNNT Films -- 11.5. Biocompatibility of BNNT Films -- 11.6. Conclusion -- References -- ch. 12 Structural and Physical Properties of Boron Nitride Nanotubes and Their Applications in Nanocomposites / Changhong Ke -- 12.1. Introduction -- 12.2. Structure and Synthesis of BNNTs -- 12.2.1. Structure of BNNTs -- 12.2.2. Synthesis of BNNTs -- 12.3. Physical Properties of BNNTs -- 12.3.1. Mechanical Properties -- 12.3.2. Electrical Properties -- 12.3.3. Thermal Properties -- 12.4. BNNT-Based Nanocomposites -- 12.5. Conclusions and Outlook -- Acknowledgments -- References -- ch. 13 Boron Nitride Nanotubes in Nanomedicine: Historical and Future Perspectives / Gianni Ciofani -- 13.1.
Contents	Brief History of Boron Nitride Nanotubes: From the Theoretical Hypothesis to the Market -- 13.2. Main Research Groups Involved in BNNT Research -- 13.3. BNNT Availability on the Market -- 13.4. Patent Analysis and Economical Implications -- 13.5. Toward the Future: Regulatory Aspects and Translational Research.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2016936856
ISBN	9780323389457
ISBN	0323389457

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