Seeking cures design of therapies for genetically determined diseases / Moyra Smith, MD, PhD, MFA.

Author/creator Smith, Moyra
Format Electronic
Publication InfoOxford ; New York : Oxford University Press, [2013]
Descriptionxi, 296 pages : illustrations ; 25 cm
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

Contents Introduction and history -- Therapy : design and general approaches -- Inborn errors of metabolism : progress in diagnosis and treatment -- Lysosomal storage diseases and therapies -- Mitochondrial function, defects and approaches to treatment -- Protein misfolding, endoplasmic reticulum stress and pathogenesis of disease -- Transporters and solute carriers : passage of molecules across membranes -- Advances in therapy for monogenic diseases -- Identifying therapeutic targets in complex, multifactorial diseases -- Approaches to cancer treatment -- Gene based molecular therapies -- Stem cells and pluripotent stem cells.
Bibliography noteIncludes bibliographical references (pages 241-282) and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2013004975
ISBN9780199915866 (hardback : alk. paper)

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