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020 a| 9781439819937 (hardcover : alk. paper);

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245 00 a| Handbook of analysis of oligonucleotides and related productsh| [electronic resource] /c| edited by Jose V. Bonilla, Susan Srivatsa.;

260 a| Boca Raton, FL :b| CRC Press,;

300 a| xiv, 497 p. ;c| 27 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| Purity analysis and impurities determination by reversed-phase HPLC / Hagen Cramer, Eric Herzberg & Kevin Finn -- Purity analysis and impurities determination by AEX-HPLC / J.R. Thayer, Veeravagu Murugaiah, Yansheng Wu -- Purity analysis and molecular weight determination by size exclusion HPLC analysis / Ming Fai Chan & Ipsita Roymoulik -- Analysis of oligonucleotides by liquid chromatography & mass spectrometry / Soheil Pourshahian & Sean McCarthy -- Sequence determination and confirmation by MS/MS and MALDI-TOF / Zoltan Timar -- Determination of melt temperature (TM) of oligonucleotides / Huihe Zhu & G. Susan Srivatsa -- Purity and content analysis of oligonucleotides by capillary gel electrophoresis / Judy Carmody and Bernhard Noll -- Bioanalysis of therapeutic oligonucleotides using hybridization-based immunoassay techniques / Sandra Carriero & Helen Legakis --;

505 0 a| Oligonucleotide assay and potency / Dennis Michaud -- Microbial analysis : endotoxin testing / Barbara J. Markley -- Analysis of residual solvents by headspace gas chromatography / Sky Countryman & Jose V. Bonilla -- Determination of extinction coefficient / Veeravagu Murugaiah -- Structural determination by NMR / Michele L. Derider, Doug Brooks & Gary Burt -- Infrared analysis of oligonucleotides / Jose V. Bonilla -- Stability indicating methods for oligonucleotide products / Veeravagu Murugaiah -- Analysis by hydrophilic interaction chromatography (HILIC) / Patrick Limbach and Renee N. Easter -- Determination of base composition / Hüseyin Aygün -- Analysis of metals in oligonucleotides / Mike Murphy -- Regulatory considerations for the development of oligonucleotide therapeutics / G. Susan Srivatsa.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Oligonucleotidesx| Analysis.=| ^A906433;

650 12 a| Oligonucleotidesx| analysis.=| ^A939630;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Bonilla, Jose V.?| UNAUTHORIZED;

700 1 a| Srivatsa, Susan.?| UNAUTHORIZED;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=773634;

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Handbook of analysis of oligonucleotides and related products / edited by Jose V. Bonilla, Susan Srivatsa.

Other author	Bonilla, Jose V.
Other author	Srivatsa, Susan.
Format	Electronic
Publication Info	Boca Raton, FL : CRC Press,
Description	xiv, 497 p. ; 27 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Oligonucleotides--Analysis. Oligonucleotides--analysis.

Contents	Purity analysis and impurities determination by reversed-phase HPLC / Hagen Cramer, Eric Herzberg & Kevin Finn -- Purity analysis and impurities determination by AEX-HPLC / J.R. Thayer, Veeravagu Murugaiah, Yansheng Wu -- Purity analysis and molecular weight determination by size exclusion HPLC analysis / Ming Fai Chan & Ipsita Roymoulik -- Analysis of oligonucleotides by liquid chromatography & mass spectrometry / Soheil Pourshahian & Sean McCarthy -- Sequence determination and confirmation by MS/MS and MALDI-TOF / Zoltan Timar -- Determination of melt temperature (TM) of oligonucleotides / Huihe Zhu & G. Susan Srivatsa -- Purity and content analysis of oligonucleotides by capillary gel electrophoresis / Judy Carmody and Bernhard Noll -- Bioanalysis of therapeutic oligonucleotides using hybridization-based immunoassay techniques / Sandra Carriero & Helen Legakis --
Contents	Oligonucleotide assay and potency / Dennis Michaud -- Microbial analysis : endotoxin testing / Barbara J. Markley -- Analysis of residual solvents by headspace gas chromatography / Sky Countryman & Jose V. Bonilla -- Determination of extinction coefficient / Veeravagu Murugaiah -- Structural determination by NMR / Michele L. Derider, Doug Brooks & Gary Burt -- Infrared analysis of oligonucleotides / Jose V. Bonilla -- Stability indicating methods for oligonucleotide products / Veeravagu Murugaiah -- Analysis by hydrophilic interaction chromatography (HILIC) / Patrick Limbach and Renee N. Easter -- Determination of base composition / Hüseyin Aygün -- Analysis of metals in oligonucleotides / Mike Murphy -- Regulatory considerations for the development of oligonucleotide therapeutics / G. Susan Srivatsa.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2010033563
ISBN	9781439819937 (hardcover : alk. paper)

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Handbook of analysis of oligonucleotides and related products / edited by Jose V. Bonilla, Susan Srivatsa.

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