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245 00 a| Pharmacology of the blood brain barrierh| [electronic resource] :b| targeting CNS disorders /c| edited by Thomas P. Davis, Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona, USA ; serial editor, S.J. Enna, Department of Molecular and Integrative Physiology, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA ; managing editor, Lynn Lecount, University of Kansas Medical Center, School of Medicine, Kansas City, Kansas, USA.;

250 a| First edition.;

260 a| Amsterdam ;b| Boston :b| Elsevier/AP,c| 2014.;

300 a| xvi, 495 pages :b| illustrations ;c| 24 cm.;

490 0 a| Advances in pharmacology ;v| volume seventy one;

504 a| Includes bibliographical references and index.;

505 0 a| 1. ABC Transporter Regulation by Signaling at the Blood-Brain Barrier: Relevance to Pharmacology -- 2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery -- 3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS -- 4. Blood-Brain Barrier Na Transporters in Ischemic Stroke -- 5. Transcytosis of Macromolecules at the Blood-Brain Barrier -- 6. Drug Delivery to the Ischemic Brain -- 7. Delivery of Chemotherapeutics Across the Blood-Brain Barrier: Challenges and Advances -- 8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood-Brain and Blood-CSF Barriers -- 9. Delivery of Therapeutic Peptides and Proteins to the CNS -- 10. Engineering and Pharmacology of Blood-Brain Barrier-Permeable Bispecific Antibodies -- 11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers -- 12. Steroids and the Blood-Brain Barrier: Therapeutic Implications -- 13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes -- 14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood-Brain Barrier in a Complex Neurological Disease -- 15. Drug Abuse and the Neurovascular Unit.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Blood-brain barrierx| Effect of drugs on.=| ^A5032;

650 0 a| Nervous systemx| Degenerationx| Chemotherapy.=| ^A6199;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Davis, Thomas P.c| (Pharmacologist)=| ^A1421121;

856 40 z| Full text available from Book Series Package - Life Sciences [BSLFSC]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbookseries%2F10543589%2F71;

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998 a| 4844072;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4844072-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 4/20/2018x| EBOOKz| JERESOURCE;

Pharmacology of the blood brain barrier targeting CNS disorders / edited by Thomas P. Davis, Department of Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona, USA ; serial editor, S.J. Enna, Department of Molecular and Integrative Physiology, Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, Kansas, USA ; managing editor, Lynn Lecount, University of Kansas Medical Center, School of Medicine, Kansas City, Kansas, USA.

Other author	Davis, Thomas P. (Pharmacologist)
Format	Electronic
Edition	First edition.
Publication Info	Amsterdam ; Boston : Elsevier/AP, 2014.
Description	xvi, 495 pages : illustrations ; 24 cm.
Supplemental Content	Full text available from Book Series Package - Life Sciences [BSLFSC]
Subjects	Blood-brain barrier--Effect of drugs on. Nervous system--Degeneration. --Chemotherapy.

Series	Advances in pharmacology ; volume seventy one
Contents	1. ABC Transporter Regulation by Signaling at the Blood-Brain Barrier: Relevance to Pharmacology -- 2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery -- 3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS -- 4. Blood-Brain Barrier Na Transporters in Ischemic Stroke -- 5. Transcytosis of Macromolecules at the Blood-Brain Barrier -- 6. Drug Delivery to the Ischemic Brain -- 7. Delivery of Chemotherapeutics Across the Blood-Brain Barrier: Challenges and Advances -- 8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood-Brain and Blood-CSF Barriers -- 9. Delivery of Therapeutic Peptides and Proteins to the CNS -- 10. Engineering and Pharmacology of Blood-Brain Barrier-Permeable Bispecific Antibodies -- 11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers -- 12. Steroids and the Blood-Brain Barrier: Therapeutic Implications -- 13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes -- 14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood-Brain Barrier in a Complex Neurological Disease -- 15. Drug Abuse and the Neurovascular Unit.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2015410625
ISBN	9780128002827 (hbk.)
ISBN	0128002824 (hbk.)

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