Immune priming in A. mellifera / by R. Starling Krentz.
| Author/creator | Krentz, R. Starling author. |
| Other author | Brewer, Michael S., degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Publication | [Greenville, N.C.] : [East Carolina University], 2017. |
| Description | 41 pages : color illustrations |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | Trans-generational immune priming (TgIP) is the transfer of maternal immune experience to progeny, producing offspring pathogen resistance and ultimately survival from infections. In colony-forming insects like the honey bee Apis mellifera, TgIP would yield a form of lasting immunity benefiting subsequent generations. TgIP has been demonstrated in multiple social insects, but the efficacy and longevity of this immune protection is yet to be fully understood. To induce "priming" we inoculated honeybee queens with Paenibacillus larvae (Pl), a spore-forming bacterium causing American Foulbrood, a brood disease that once plagued beekeepers worldwide. Following inoculation, offspring of "primed" queens were fed a diet containing P. larvae spores and mortality rates were measured to assess TGIP. Our data reflects a dramatic reduction in larval mortality in A. mellifera colonies with "primed" queens, and demonstrates the efficacy of this protection at multiple timepoints. |
| General note | Presented to the faculty of the Department of Biology |
| General note | Advisor: Michael Brewer |
| General note | Title from PDF t.p. (viewed February 22, 2018). |
| Dissertation note | M.S. East Carolina University 2017. |
| Bibliography note | Includes bibliographical references. |
| Technical details | System requirements: Adobe Reader. |
| Technical details | Mode of access: World Wide Web. |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |