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010 a| 2010554341;

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020 a| 9789241530743;

020 a| 924153074X;

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049 a| EREEa| NEHH;

050 00 a| RA1242.C87b| K54 2008;

100 1 a| Kielhorn, J.?| UNAUTHORIZED;

245 10 a| 2-butenalh| [electronic resource] /c| first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis.;

246 3 a| Two-butenal;

260 a| Geneva :b| World Health Organization,;

300 a| vi, 47 p. :b| ill.;

490 1 a| Concise international chemical assessment document,x| 1020-6167 ;v| 74;

500 a| "IPCS, International Programme on Chemical Safety"--Cover.;

500 a| "Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals.";

504 a| Includes bibliographical references (p. 32-38).;

505 2 a| Identity and physical/chemical properties -- Analytical methods -- Sources of human and environmental exposure -- Environmental transport, distribution, transformation and accumulation -- Environmental levels and human exposure -- Comparative kinetics and metabolism in laboratory animals and humans -- Effects on laboratory mammals and in vitro test systems -- Effects on humans -- Effects on other organisms in the laboratory and field -- Effects evaluation -- Previous evaluations by IOMC bodies.;

506 a| Available only to authorized users.;

520 a| 2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.--Publisher's description.;

530 a| Also freely available online.;

538 a| Mode of access: World Wide Web;

546 a| Summaries in French and Spanish.;

650 0 a| Crotonaldehydex| Environmental aspects.?| UNAUTHORIZED;

650 0 a| Crotonaldehydex| Toxicology.?| UNAUTHORIZED;

650 0 a| Crotonaldehydex| Physiological effect.?| UNAUTHORIZED;

650 12 a| Aldehydesx| adverse effects.?| UNAUTHORIZED;

650 22 a| Aldehydesx| pharmacokinetics.?| UNAUTHORIZED;

650 22 a| Aldehydesx| toxicity.=| ^A956987;

650 22 a| Environmental Exposure.=| ^A919733;

650 22 a| Risk Assessment.=| ^A929045;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Mangelsdorf, I.?| UNAUTHORIZED;

700 1 a| Ziegler-Skylakakis, K.?| UNAUTHORIZED;

710 2 a| World Health Organization.=| ^A1132;

710 2 a| United Nations Environment Programme.=| ^A14687;

710 2 a| International Labour Organisation.=| ^A14707;

710 2 a| International Program on Chemical Safety.=| ^A13876;

710 2 a| Inter-Organization Programme for the Sound Management of Chemicals.=| ^A460860;

830 0 a| Concise international chemical assessment document ;v| 74.?| UNAUTHORIZED;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=456315;

947 a| (OCoLC)ocn316604714;

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949 a| CLICK ON WEB ADDRESSw| ASISh| JMUSIC60;

596 a| 1 3 4;

998 a| 4665383;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4665383-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 3/19/2017x| EBOOKz| JERESOURCE;

2-butenal / first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis.

Author/creator	Kielhorn, J.
Format	Electronic
Publication Info	Geneva : World Health Organization,
Description	vi, 47 p. : ill.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Crotonaldehyde--Environmental aspects. Crotonaldehyde--Toxicology. Crotonaldehyde--Physiological effect. Aldehydes--adverse effects. Aldehydes--pharmacokinetics. Aldehydes--toxicity. Environmental Exposure. Risk Assessment.

Other author/creator	Mangelsdorf, I.
Other author/creator	Ziegler-Skylakakis, K.
Other author/creator	World Health Organization.
Other author/creator	United Nations Environment Programme.
Other author/creator	International Labour Organisation.
Other author/creator	International Program on Chemical Safety.
Other author/creator	Inter-Organization Programme for the Sound Management of Chemicals.
Variant title	Two-butenal
Series	Concise international chemical assessment document, 1020-6167 ; 74 Concise international chemical assessment document ; 74. UNAUTHORIZED
Partial contents	Identity and physical/chemical properties -- Analytical methods -- Sources of human and environmental exposure -- Environmental transport, distribution, transformation and accumulation -- Environmental levels and human exposure -- Comparative kinetics and metabolism in laboratory animals and humans -- Effects on laboratory mammals and in vitro test systems -- Effects on humans -- Effects on other organisms in the laboratory and field -- Effects evaluation -- Previous evaluations by IOMC bodies.
Abstract	2-Butenal (also known as crotonaldehyde) is an ab-unsaturated aldehyde and consequently a very reactive compound. It is a chemical intermediate used chiefly in the manufacture of sorbates, solvents, and, to a lesser extent, pharmaceutical products and aroma chemicals. This publication studies the pharmacokinetics, environmental exposure, chemical toxicology and carcinogenicity of 2-butenal. However, to enable an understanding and evaluation of this aldehyde in the context of environmental health, other aldehydes, such as formaldehyde, acetaldehyde, and acrolein, are mentioned for comparison.--Publisher's description.
General note	"IPCS, International Programme on Chemical Safety"--Cover.
General note	"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organization, and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."
Bibliography note	Includes bibliographical references (p. 32-38).
Access restriction	Available only to authorized users.
Other forms	Also freely available online.
Technical details	Mode of access: World Wide Web
Language	Summaries in French and Spanish.
Genre/form	Electronic books.
LCCN	2010554341
ISBN	9789241530743
ISBN	924153074X

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2-butenal / first draft prepared by J. Kielborn and I. Mangelsdorf ; and K. Ziegler-Skylakakis.

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