Tools

LEADER 04199cam a2200601Ii 4500

001 ocn968303070;

003 OCoLC;

005 20170427122742.0;

006 m o d ;

007 cr unu||||||||;

008 170113s2016 ncuab obm 000 0 eng d;

035 a| (Sirsi) o968303070;

035 a| (OCoLC)968303070;

049 a| EREE;

090 a| QL638.G27;

100 1 a| Newsome, William Burns,e| author.?| UNAUTHORIZED;

245 10 a| Gene expression and the evolution of reduced sexual dimorphism in a threespine stickleback color trait /c| by William Burns Newsome.;

264 1 a| [Greenville, N.C.] :b| [East Carolina University],c| 2016.;

300 a| 69 pages :b| illustrations (chiefly color), maps;

336 a| textb| txt2| rdacontent;

337 a| computerb| c2| rdamedia;

338 a| online resourceb| cr2| rdacarrier;

347 a| text fileb| PDFc| 1.33 MB2| rda;

538 a| System requirements: Adobe Reader.;

538 a| Mode of access: World Wide Web.;

502 b| M.S.c| East Carolina Universityd| 2016.;

500 a| Presented to the faculty of the Department of Biology.;

500 a| Advisor: Jeffrey S. McKinnon.;

500 a| Advisor: Christopher Balakrishnan.;

500 a| Title from PDF t.p. (viewed January 31, 2017).;

520 3 a| Elucidating the processes and mechanisms responsible for sexual dimorphism has been a central task for evolutionary biologists since Darwin first proposed the concept of sexual selection. However, our understanding of the genetic basis for variation in sexual dimorphism remains notably incomplete. Here we used a well-established evolutionary model, the threespine stickleback, to examine the genomic basis for variation in orange-red throat coloration, a trait long thought confined to males, and outline broad genetic patterns among and between populations where females have adopted this male-typical trait. Specifically, RNA-Seq was performed on stickleback throat and brain tissues from five populations: two expressing standard sexual dimorphism for throat coloration (red males and relatively dull females) and three expressing chromatic monomorphism (two where both sexes express red throat coloration, one where both largely lack this trait). We find that chromatically monomorphic populations show an overall decrease in sexually dimorphic gene expression, in both populations in throat tissue and in only one in brain tissue, relative to fish from standard sexually dimorphic populations. Variation in this trait is substantial between populations, tissues, and sets of sex-biased genes, and populations with red females appear to have independently converged onto a similar phenotype by separate genetic mechanisms. Additionally, we identified roles for melanin signaling pathways in throat tissue and, although no carotenoid pathways were enriched, a handful of carotenoid related genes were differentially expressed. These results appear to suggest that an overall decrease in sexual dimorphism, replicated independently in two geographically distinct populations, accompanies the rise of a male-typical trait in female sticklebacks.;

504 a| Includes bibliographical references.;

650 0 a| Threespine sticklebackx| Genetics.=| ^A93264;

650 0 a| Sexual dimorphism (Animals)=| ^A9115;

650 0 a| Evolutionary developmental biology.=| ^A1195156;

650 0 a| Gene expression.=| ^A6250;

653 a| RNA-Seq;

653 a| Gasterosteus aculeatus;

653 a| Masculinization;

653 a| Color Polymorphism;

653 a| Carotenoid;

653 a| Throat Color;

700 1 a| McKinnon, Jeffrey.,e| degree supervisor.=| ^A1478316;

700 1 a| Balakrishnan, Chris,e| degree supervisor.=| ^A1478344;

710 2 a| East Carolina University.b| Department of Biology.=| ^A637467;

856 40 z| Access via ScholarShipu| http://hdl.handle.net/10342/6017;

949 o| wjh;

994 a| C0b| ERE;

596 a| 1 4;

998 a| 4604951;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4604951-1001l| JNETm| JOYNERr| Ys| Yt| JNE3ETDu| 1/13/2017x| ETDz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4604951-2001l| HSLELECm| HSLr| Ys| Yt| HEETDu| 1/13/2017x| ETDz| HERESOURCE;

Gene expression and the evolution of reduced sexual dimorphism in a threespine stickleback color trait / by William Burns Newsome.

Author/creator	Newsome, William Burns author.
Other author	McKinnon, Jeffrey., degree supervisor.
Other author	Balakrishnan, Chris, degree supervisor.
Other author	East Carolina University. Department of Biology.
Format	Theses and dissertations
Publication	[Greenville, N.C.] : [East Carolina University], 2016.
Description	69 pages : illustrations (chiefly color), maps
Supplemental Content	Access via ScholarShip
Subjects	Threespine stickleback--Genetics. Sexual dimorphism (Animals) Evolutionary developmental biology. Gene expression.

Summary	Elucidating the processes and mechanisms responsible for sexual dimorphism has been a central task for evolutionary biologists since Darwin first proposed the concept of sexual selection. However, our understanding of the genetic basis for variation in sexual dimorphism remains notably incomplete. Here we used a well-established evolutionary model, the threespine stickleback, to examine the genomic basis for variation in orange-red throat coloration, a trait long thought confined to males, and outline broad genetic patterns among and between populations where females have adopted this male-typical trait. Specifically, RNA-Seq was performed on stickleback throat and brain tissues from five populations: two expressing standard sexual dimorphism for throat coloration (red males and relatively dull females) and three expressing chromatic monomorphism (two where both sexes express red throat coloration, one where both largely lack this trait). We find that chromatically monomorphic populations show an overall decrease in sexually dimorphic gene expression, in both populations in throat tissue and in only one in brain tissue, relative to fish from standard sexually dimorphic populations. Variation in this trait is substantial between populations, tissues, and sets of sex-biased genes, and populations with red females appear to have independently converged onto a similar phenotype by separate genetic mechanisms. Additionally, we identified roles for melanin signaling pathways in throat tissue and, although no carotenoid pathways were enriched, a handful of carotenoid related genes were differentially expressed. These results appear to suggest that an overall decrease in sexual dimorphism, replicated independently in two geographically distinct populations, accompanies the rise of a male-typical trait in female sticklebacks.
General note	Presented to the faculty of the Department of Biology.
General note	Advisor: Jeffrey S. McKinnon.
General note	Advisor: Christopher Balakrishnan.
General note	Title from PDF t.p. (viewed January 31, 2017).
Dissertation note	M.S. East Carolina University 2016.
Bibliography note	Includes bibliographical references.
Technical details	System requirements: Adobe Reader.
Technical details	Mode of access: World Wide Web.

Availability

Library	Location	Call Number	Status	Item Actions
	Electronic Resources	Access Content Online	✔ Available

Gene expression and the evolution of reduced sexual dimorphism in a threespine stickleback color trait / by William Burns Newsome.

Click here for more information about this title

Availability