Apoptosis and development / edited by Hermann Steller.

Other author Steller, Hermann.
Format Electronic
EditionFirst edition.
Publication InfoAmsterdam : Elsevier/Academic Press, 2015.
Descriptionxvi, 374 pages, 22 unnumbered pages : illustrations (some color), charts (some color) ; 24 cm.
Supplemental ContentFull text available from Book Series Package - Life Sciences [BSLFSC]
Subjects

SeriesCurrent topics in developmental biology, 0070-2153 ; volume 114
Current topics in developmental biology v. 114. 0070-2153 ^A926884
Contents 1. Cell death in C. elegans development / Jennifer Zuckerman Malin and Shai Shaham -- 2. Mitochondrial cell death pathways in Caenorhabiditis elegans / Mahendra Seervi and Ding Xue -- 3. Autophagy in cell life and cell death / Allyson L. Anding and Eric H. Baehrecke -- 4. The end of the beginning: cell death in the germline / Jeanne S. Peterson, Allison K. Timmons, Albert A. Mondragon, and Kimberly McCall -- 5. The HOX-apoptosis regulatory interplay in development and disease / Katrin Domsch, Fani Papagiannouli, and Ingrid Lohmann -- 6. Programmed cell death and caspase functions during neural development / Yoshifumi Yamaguchi and Masayuki Miura -- 7. Regulation of cell death by IAPs and their antagonists/ Deepika Vasudevan and Hyung Don Ryoo -- 8. Ubiquitin-Mediated regulation of cell death, inflammation, and defense of homeostasis / Pascal Meier, Otto Morris, and Meike Broemer -- 9. The sound of silence: signaling by apoptotic cells / Caitlin E. Fogarty and Andreas Bergmann -- 10. Clearance of apoptotic cells and pyrenocytes / Satoshi Toda, Chihiro Nishi, Yuichi Yanagihashi, Katsumori Segawa, an Shigekazu Natgata -- 11. Apoptotic cell clearance in development / Jeny Shklover, Flonia Levy-Adam, and Estee Kurant -- 12. The morphogenetic role of apoptosis / Bruno Monier and Magali Suzanne.
Abstract "Programmed cell death (PCD) plays important roles in animal development, and its original discovery dates back to 1842 when Karl Vogt reported that cell death is associated with removal of the notochord during amphibian metamorphosis. During the past two decades, dramatic progress has been made in understanding the biochemical basis of the most prominent form of naturally occurring PCD, termed apoptosis. This volume illustrates both the remarkable advances that have been made in elucidating pathways and detailed biochemical mechanisms to explain key events during apoptosis, but they also reveal the many unresolved questions and unexpected new opportunities that we still face for understanding the physiological regulation and function of PCD." --Back Cover.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
ISBN9780124104259
ISBN0124104258

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