The unfolded protein response and cellular stress. / edited by P. Michael Conn.
| Other author | Conn, P. Michael. |
| Format | Electronic |
| Edition | 1st ed. |
| Publication Info | San Diego, CA : Elsevier/Academic Press, |
| Description | xlvii, 384 p., [8] p. of plates : ill. (some col.) ; 24 cm. |
| Supplemental Content | Full text available from Methods in Enzymology |
| Supplemental Content | Full text available from ScienceDirect Enzymology Book Series |
| Subjects |
| Series | Methods in enzymology, 0076-6879 ; v. 490 Methods in enzymology v. 490. 0076-6879 ^A497553 |
| Contents | Methods for investigating the UPR in filamentous fungi -- Assays for detecting the unfolded protein response -- Analysis of the role of nerve growth factor in promoting cell survival during endoplasmic reticulum stress in PC12 cells -- Measuring ER stress and the unfolded protein response using mammalian tissue culture system -- Real-time monitoring of ER stress in living cells and animals using ESTRAP assay -- HIV protease inhibitors induce endoplasmic reticulum stress and disrupt barrier integrity in intestinal epithelial cells -- Dexamethasone induction of a heat stress response -- Detecting and quantitating physiological endoplasmic reticulum stress -- PI 3-kinase regulatory subunits as regulators of the unfolded protein response -- The emerging role of histone deacetylases (HDACs) in UPR regulation -- Immunohistochemical detection of activating transcription factor 3, a hub of the cellular adaptive-response network -- Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins -- Measurement and modification of the expression level of the chaperone protein and signaling regulator GRP78/BiP in mammalian cells -- The endoplasmic reticulum-associated degradation and disulfide reductase ERdj5 -- Structural insight into the protective role of P58(IPK) during unfolded protein response -- Principles of IRE1 modulation using chemical tools -- Methods to study stromal-cell derived factor 2 in the context of ER stress and the unfolded protein response in Arabidopsis thaliana -- Nitrosative stress-induced S-glutathionylation of protein disulfide isomerase -- Methods for analyzing eIF2 kinases and translational control in the unfolded protein response. |
| Bibliography note | Includes bibliographical references and indexes. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| ISBN | 012385928X |
| ISBN | 9780123859280 |
| ISBN | 0123851149 |
| ISBN | 9780123851147 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | ✔ Available |