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020 a| 9780521887328 (hardback);

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245 00 a| Recombinant antibodies for immunotherapyh| [electronic resource] /c| edited by Melvyn Little.;

260 a| New York :b| Cambridge University Press,;

300 a| xiv, 419 p. :b| ill. (some col.) ;c| 27 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| Humanization of recombinant antibodies / José W. Saldanha -- Immunogenicity assessment of antibody therapeutics / Philippe Stas ... [et al.] -- In vitro screening for antibody immunogenicity / Frank J. Carr and Matthew B. Baker -- Antibody libraries from naïve V gene sources / Gerald Beste and David Lowe -- Antibodies from IgM libraries / Stefan Knackmuss and Vera Molkenthin -- Generation and screening of synthetic human combinatorial antibody library HuCAL GOLD / Ingo M. Klagge -- Therapeutic antibodies from XenoMouse transgenic mice / Aya Jakobovits -- VelocImmune : immunoglobulin variable region humanized mice / Andrew Murphy -- Mechanisms of tumour cell killing by therapeutic antibodies / Ross Stewart and Carl Webster -- Optimization of Fc domains to enhance antibody therapeutics / Greg A. Lazar and Aaron K. Chamberlain -- Glycoengineered therapeutic antibodies / Peter Brünker, Peter Sondermann, and Pablo Umaña -- Monoclonal antibodies for the delivery of cytotoxic drugs / David J. King --;

505 0 a| Immunotherapy with radio-immune conjugates / Christina A. Kousparou and Agamemnon A. Epenetos -- Immunotherapeutic antibody fusion proteins / Nigel S. Courtenay-Luck and David Jones -- Alternative antibody formats / Fabrice Le Gall and Melvyn Little -- Single-domain antibodies / Serge Muyldermans, Gholamreza Hassanzadeh Ghassabeh, and Dirk Saerens -- Engineering of non-CDR loops in immunoglobulin domains / Florian Rüker and Gordana Wozniak-Knopp -- Alternative scaffolds : expanding the options of antibodies / Andreas Plückthun -- Polymer fusions to increase antibody half-lives : PEGylation and other modifications / Sam P. Heywood and David P. Humphreys -- Extending antibody half-lives with albumin / Jan Terje Andersen and Inger Sandlie -- A stem cell-based platform for the discovery and development of antitumor therapeutic antibodies to novel targets / Jennie P. Mather ... [et al.] -- Antibody directed enzyme prodrug therapy (ADEPT) / Helen L. Lowe ... [et al.] -- Immune privilege and tolerance - therapeutic antibody approaches / Daron Forman ... [et al.] -- Antibody therapeutics : business achievements and business outlook / Christophe Bourrilly.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Monoclonal antibodiesx| Therapeutic use.=| ^A1017851;

650 12 a| Immunotherapyx| methods.=| ^A925715;

650 22 a| Antibodies, Monoclonalx| therapeutic use.=| ^A922995;

650 22 a| Recombinant Proteinsx| therapeutic use.=| ^A956547;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Little, Melvyn,d| 1945-=| ^A98116;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=452000;

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Recombinant antibodies for immunotherapy / edited by Melvyn Little.

Other author	Little, Melvyn, 1945-
Format	Electronic
Publication Info	New York : Cambridge University Press,
Description	xiv, 419 p. : ill. (some col.) ; 27 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Monoclonal antibodies--Therapeutic use. Immunotherapy--methods. Antibodies, Monoclonal--therapeutic use. Recombinant Proteins--therapeutic use.

Contents	Humanization of recombinant antibodies / José W. Saldanha -- Immunogenicity assessment of antibody therapeutics / Philippe Stas ... [et al.] -- In vitro screening for antibody immunogenicity / Frank J. Carr and Matthew B. Baker -- Antibody libraries from naïve V gene sources / Gerald Beste and David Lowe -- Antibodies from IgM libraries / Stefan Knackmuss and Vera Molkenthin -- Generation and screening of synthetic human combinatorial antibody library HuCAL GOLD / Ingo M. Klagge -- Therapeutic antibodies from XenoMouse transgenic mice / Aya Jakobovits -- VelocImmune : immunoglobulin variable region humanized mice / Andrew Murphy -- Mechanisms of tumour cell killing by therapeutic antibodies / Ross Stewart and Carl Webster -- Optimization of Fc domains to enhance antibody therapeutics / Greg A. Lazar and Aaron K. Chamberlain -- Glycoengineered therapeutic antibodies / Peter Brünker, Peter Sondermann, and Pablo Umaña -- Monoclonal antibodies for the delivery of cytotoxic drugs / David J. King --
Contents	Immunotherapy with radio-immune conjugates / Christina A. Kousparou and Agamemnon A. Epenetos -- Immunotherapeutic antibody fusion proteins / Nigel S. Courtenay-Luck and David Jones -- Alternative antibody formats / Fabrice Le Gall and Melvyn Little -- Single-domain antibodies / Serge Muyldermans, Gholamreza Hassanzadeh Ghassabeh, and Dirk Saerens -- Engineering of non-CDR loops in immunoglobulin domains / Florian Rüker and Gordana Wozniak-Knopp -- Alternative scaffolds : expanding the options of antibodies / Andreas Plückthun -- Polymer fusions to increase antibody half-lives : PEGylation and other modifications / Sam P. Heywood and David P. Humphreys -- Extending antibody half-lives with albumin / Jan Terje Andersen and Inger Sandlie -- A stem cell-based platform for the discovery and development of antitumor therapeutic antibodies to novel targets / Jennie P. Mather ... [et al.] -- Antibody directed enzyme prodrug therapy (ADEPT) / Helen L. Lowe ... [et al.] -- Immune privilege and tolerance - therapeutic antibody approaches / Daron Forman ... [et al.] -- Antibody therapeutics : business achievements and business outlook / Christophe Bourrilly.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2008044201
ISBN	9780521887328 (hardback)
ISBN	0521887321 (hardback)

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