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245 04 a| The maternal-to-zygotic transitionh| [electronic resource] /c| edited by Howard D. Lipshitz, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.;

250 a| First edition.;

260 a| Amsterdam :b| Elsevier/AP, Academic Press is an impint of Elsevier,c| 2015.;

300 a| xiii, 415 pages, 18 unnumbered pages of color plates :b| illustrations ;c| 24 cm.;

490 1 a| Current topics in developmental biology,x| 0070-2153 ;v| volume 113;

504 a| Includes bibliographical references and index.;

505 0 a| The maternal-to-zygotic transition in C. elegans / Scott Robertson and Rueyling Lin. Introduction ; Components of the MZT ; Major regulators/events that coordinate the MZT ; Concluding remarks -- Regulation and function of maternal gene products during the maternal-to-zygotic transition in Drosophila / John D. Laver [and others] ; Introduction ; Overview of oogenesis and early embryogenesis ; Maternal factors during oocyte maturation ; Maternal factors during egg activation and early embryogenesis ; The maternal-to-zygotic transition in primordial germ cells ; Conclusion and future prospects -- Transcriptional activation of the zygotic genome in Drosophila / Melissa M. Harrison and Michael B. Eisen. Introduction ; Activating transcription of the zygotic genome ; Mechanisms regulating transcriptional activation during the MZT ; Chromatin dynamics during the MZT ; The role of cis-Regulatory elements in regulating zygotic transcription ; Concluding remarks -- Coordinating cell cycle remodeling with transcriptional activation at the Drosophila MBT / Shelby A. Blythe and Eric F. Wieschaus. Introduction ; What happens at the MBT? ; Mechanisms for timing zygotic genome activation ; Concluding remarks -- Germ line versus soma in the transition from egg to embryo / S. Zachary Swartz and Gary M. Wessel. The big picture ; Are METs universal? ; General activation of the embryonic genome ; Activation of regionally specific gene regulatory networks ; Loss of cleavage synchrony : a cause of effect of embryonic control? ; Degradation of the maternally supplied transcription ; Separating the soma from the germ line : a critical fork in the road ; Different roads lead to a conserved germ line program ; PGC specification by induction ; PGC specification by preloading ; Evolutionary transition of PGC segregation in the echinoderms ; Putting your germ cells in the freezer : possible advantages for preloaded specification ; Are METs different between the germ line and soma? : transcriptional repression in PGCs ; Differential stability of mRNA in the germ line and soma ; NMETs are delayed in PGCs ; A continuum of maternal and embryonic contributions to development -- The maternal-to-zygotic transition during vertebrate development : a model for reprogramming / Valeria Yartseva and Antonio J. Giraldez. Introduction ; Mechanisms to maternal mRNA clearance during the MZT ; Consequences of failure of maternal mRNA clearance ; MZT connection to other transitions and reprogramming ; Concluding remarks -- Building the future : post-transcriptional regulation of cell fate decisions prior to the Xenopus midblastula transition / Michael D. Sheets. Introduction ; Regulation of maternal mRNAs in the Xenopus embryo ; miRNA regulation of mRNAs during early Xenopus development ; Translational control of mRNAs encoding cell fate determinants -- Regulation of maternal proteins in the Xenopus embryo ; Regulated proteolysis and the control of maternal signaling pathways ; The Xenopus maternal proteome ; The maternal phosphoproteome ; Metabolism and metabolomics ; Conclusions -- The Xenopus maternal-to-zygotic transition from the perspective of the germline / Jing Yang [and others]. Introduction ; Germ-plasm RNAs and cytoskeletal dynamics : stage VI Oocyte ; Germ plasm and cytoskeletal dynamics : oocyte maturation/fertilization ; Maternal determinants for two lineages inherited by the same blastomeres : a dilemma ; Mechanisms for protecting the germline during the MZT ; PGCs are transcriptionally repressed at the MBT ; How does the germline escape the MBT? ; RNA degradation during the MZT ; Stability of germline RNAs and proteins ; The PGC late-gastrula transition -- Sculpting the transcriptome during the oocyte-to-embryo transition in mouse / Petr Svoboda [and others]. Introduction ; Overview of significant events during OET ; The OET : the mother of all transcriptome remodeling -- The maternal-to-zygotic transition in flowering plants : evidence, mechanisms, and plasticity / Celia Baroux and Ueli Grossniklaus. Seed development ; a largely maternal affair ; Emancipation of the plant embryo ; Progressive zygotic gene activation ; Mechanisms of zygotic genome activation ; The dynamics of the maternal-to-zygotic transition vary depending on plant species and genetic background ; Biological functions of the maternal-to-zygotic transition in plants ; Unresolved questions and outlook -- the maternal-to-zygotic transition in higher plants : available approaches, critical limitations, and technical requirements / Peng Zhao and Meng-Xiang Sun. Zygote development and embryogenesis in angiosperms ; The MZT during early angiosperm embryogenesis ; Studies on the MZT during embryogeneis and technical limitations ; Current techniques used to study the MZT in higher plants ; Conclusions and perspectives.;

505 00 t| The maternal-to-zygotic transition in C. elegans /r| Scott Robertson and Rueyling Lin --t| Regulation and function of maternal gene products during the maternal-to-zygotic transition in Drosophila /r| John D. Laver, Alexander J. Marsolais, Craig A. Smibert, and Howard D. Lipshitz --t| Transcriptional activation of the zygotic genome in Drosophila /r| Melissa M. Harrison and Michael B. Eisen --t| Coordinating cell cycle remodeling with transcriptional activation at the Drosophila MBT /r| Shelby A. Blythe and Eric F. Wieschaus --t| Germ line versus soma in the transition from egg to embryo /r| S. Zachary Swartz and Gary M. Wessel --t| The maternal-to-zygotic transition during vertebrate development : a model for reprogramming /r| Valeria Yartseva and Antonio J. Giraldez --t| Building the future : post-transcriptional regulation of cell fate decisions prior to the Xenopus midblastula transition /r| Michael D. Sheets --t| The Xenopus maternal-to-zygotic transition from the perspective of the germline /r| Jing Yang, Tristan Aguero, and Mary Lou King --t| Sculpting the transcriptome during the oocyte-to-embryo transition in mouse /r| Petr Svoboda, Vedran Franke, and Richard M. Schultz --t| The maternal-to-zygotic transition in flowering plants : evidence, mechanisms, and plasticity /r| Célia Baroux and Ueli Grossniklaus --t| The maternal-to-zygotic transition in higher plants : available approaches, critical limitations, and technical requirements /r| Peng Zhao and Meng-Xiang Sun.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Developmental genetics.=| ^A2944;

650 0 a| Molecular biology.=| ^A1446;

650 12 a| Transcription, Genetic=| ^A922115;

650 22 a| Gene Expression Regulation, Developmental=| ^A1004888;

650 22 a| Genes, Developmental?| UNAUTHORIZED;

650 22 a| Zygotex| metabolism=| ^A1337037;

650 22 a| Transcription Factors=| ^A928861;

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650 7 a| Molecular biology.2| fast0| (OCoLC)fst01024734;

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700 1 a| Lipshitz, Howard D.?| UNAUTHORIZED;

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830 0 a| Current topics in developmental biologyv| v. 113.x| 0070-2153=| ^A926884;

856 40 z| Full text available from Book Series Package - Life Sciences [BSLFSC]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbookseries%2F00702153%2F113;

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The maternal-to-zygotic transition / edited by Howard D. Lipshitz, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

Other author	Lipshitz, Howard D.
Format	Electronic
Edition	First edition.
Publication Info	Amsterdam : Elsevier/AP, Academic Press is an impint of Elsevier, 2015.
Description	xiii, 415 pages, 18 unnumbered pages of color plates : illustrations ; 24 cm.
Supplemental Content	Full text available from Book Series Package - Life Sciences [BSLFSC]
Subjects	Developmental genetics. Molecular biology. Transcription, Genetic Gene Expression Regulation, Developmental Genes, Developmental Zygote--metabolism. Transcription Factors

Series	Current topics in developmental biology, 0070-2153 ; volume 113 Current topics in developmental biology v. 113. 0070-2153 ^A926884
Contents	The maternal-to-zygotic transition in C. elegans / Scott Robertson and Rueyling Lin. Introduction ; Components of the MZT ; Major regulators/events that coordinate the MZT ; Concluding remarks -- Regulation and function of maternal gene products during the maternal-to-zygotic transition in Drosophila / John D. Laver [and others] ; Introduction ; Overview of oogenesis and early embryogenesis ; Maternal factors during oocyte maturation ; Maternal factors during egg activation and early embryogenesis ; The maternal-to-zygotic transition in primordial germ cells ; Conclusion and future prospects -- Transcriptional activation of the zygotic genome in Drosophila / Melissa M. Harrison and Michael B. Eisen. Introduction ; Activating transcription of the zygotic genome ; Mechanisms regulating transcriptional activation during the MZT ; Chromatin dynamics during the MZT ; The role of cis-Regulatory elements in regulating zygotic transcription ; Concluding remarks -- Coordinating cell cycle remodeling with transcriptional activation at the Drosophila MBT / Shelby A. Blythe and Eric F. Wieschaus. Introduction ; What happens at the MBT? ; Mechanisms for timing zygotic genome activation ; Concluding remarks -- Germ line versus soma in the transition from egg to embryo / S. Zachary Swartz and Gary M. Wessel. The big picture ; Are METs universal? ; General activation of the embryonic genome ; Activation of regionally specific gene regulatory networks ; Loss of cleavage synchrony : a cause of effect of embryonic control? ; Degradation of the maternally supplied transcription ; Separating the soma from the germ line : a critical fork in the road ; Different roads lead to a conserved germ line program ; PGC specification by induction ; PGC specification by preloading ; Evolutionary transition of PGC segregation in the echinoderms ; Putting your germ cells in the freezer : possible advantages for preloaded specification ; Are METs different between the germ line and soma? : transcriptional repression in PGCs ; Differential stability of mRNA in the germ line and soma ; NMETs are delayed in PGCs ; A continuum of maternal and embryonic contributions to development -- The maternal-to-zygotic transition during vertebrate development : a model for reprogramming / Valeria Yartseva and Antonio J. Giraldez. Introduction ; Mechanisms to maternal mRNA clearance during the MZT ; Consequences of failure of maternal mRNA clearance ; MZT connection to other transitions and reprogramming ; Concluding remarks -- Building the future : post-transcriptional regulation of cell fate decisions prior to the Xenopus midblastula transition / Michael D. Sheets. Introduction ; Regulation of maternal mRNAs in the Xenopus embryo ; miRNA regulation of mRNAs during early Xenopus development ; Translational control of mRNAs encoding cell fate determinants -- Regulation of maternal proteins in the Xenopus embryo ; Regulated proteolysis and the control of maternal signaling pathways ; The Xenopus maternal proteome ; The maternal phosphoproteome ; Metabolism and metabolomics ; Conclusions -- The Xenopus maternal-to-zygotic transition from the perspective of the germline / Jing Yang [and others]. Introduction ; Germ-plasm RNAs and cytoskeletal dynamics : stage VI Oocyte ; Germ plasm and cytoskeletal dynamics : oocyte maturation/fertilization ; Maternal determinants for two lineages inherited by the same blastomeres : a dilemma ; Mechanisms for protecting the germline during the MZT ; PGCs are transcriptionally repressed at the MBT ; How does the germline escape the MBT? ; RNA degradation during the MZT ; Stability of germline RNAs and proteins ; The PGC late-gastrula transition -- Sculpting the transcriptome during the oocyte-to-embryo transition in mouse / Petr Svoboda [and others]. Introduction ; Overview of significant events during OET ; The OET : the mother of all transcriptome remodeling -- The maternal-to-zygotic transition in flowering plants : evidence, mechanisms, and plasticity / Celia Baroux and Ueli Grossniklaus. Seed development ; a largely maternal affair ; Emancipation of the plant embryo ; Progressive zygotic gene activation ; Mechanisms of zygotic genome activation ; The dynamics of the maternal-to-zygotic transition vary depending on plant species and genetic background ; Biological functions of the maternal-to-zygotic transition in plants ; Unresolved questions and outlook -- the maternal-to-zygotic transition in higher plants : available approaches, critical limitations, and technical requirements / Peng Zhao and Meng-Xiang Sun. Zygote development and embryogenesis in angiosperms ; The MZT during early angiosperm embryogenesis ; Studies on the MZT during embryogeneis and technical limitations ; Current techniques used to study the MZT in higher plants ; Conclusions and perspectives.
Contents	The maternal-to-zygotic transition in C. elegans / Scott Robertson and Rueyling Lin -- Regulation and function of maternal gene products during the maternal-to-zygotic transition in Drosophila / John D. Laver, Alexander J. Marsolais, Craig A. Smibert, and Howard D. Lipshitz -- Transcriptional activation of the zygotic genome in Drosophila / Melissa M. Harrison and Michael B. Eisen -- Coordinating cell cycle remodeling with transcriptional activation at the Drosophila MBT / Shelby A. Blythe and Eric F. Wieschaus -- Germ line versus soma in the transition from egg to embryo / S. Zachary Swartz and Gary M. Wessel -- The maternal-to-zygotic transition during vertebrate development : a model for reprogramming / Valeria Yartseva and Antonio J. Giraldez -- Building the future : post-transcriptional regulation of cell fate decisions prior to the Xenopus midblastula transition / Michael D. Sheets -- The Xenopus maternal-to-zygotic transition from the perspective of the germline / Jing Yang, Tristan Aguero, and Mary Lou King -- Sculpting the transcriptome during the oocyte-to-embryo transition in mouse / Petr Svoboda, Vedran Franke, and Richard M. Schultz -- The maternal-to-zygotic transition in flowering plants : evidence, mechanisms, and plasticity / Célia Baroux and Ueli Grossniklaus -- The maternal-to-zygotic transition in higher plants : available approaches, critical limitations, and technical requirements / Peng Zhao and Meng-Xiang Sun.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2016499256
ISBN	9780124095236
ISBN	0124095232

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The maternal-to-zygotic transition / edited by Howard D. Lipshitz, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.

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