Influence of testosterone on comb development in embryonic and young chicks / by Thomas Manning Holt.
| Author/creator | Holt, Thomas Manning author. |
| Other author | Lawrence, Irvin E., Jr., degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Production | 1968. |
| Description | 67 leaves : illustrations ; 28 cm |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | Chick embryos of the White Leghorn breed were subjected to testosterone-propionate from the 6-6 1/2 day of incubation (stage 29) through the 20-21 day (stage 46), and from hatching through the 4th, 6th, 10th, and 17th days of age. The influence of testosterone on comb morpho genesis was determined by histological and histochemical analyses of comb organs removed at each developmental stage. Data accumulated in this study indicate that embryonic comb fibroblasts and adipose cells are sufficiently differentiated to respond to testosterone applications at an earlier stage than normally occurs during comb development. Structural materials such as collagen, reticulum precursors and lipids were observed in testosterone treated combs before controls. Other components, e.g., mucopolysaccharides, however, demonstrated more complex assimilation patterns in response to the hormone. During normal and hormonally stimulated comb growth the production of mucoidal ground substance and collagen fibers proceeded from the base of the comb upward, while overall organ growth was observed to progress along a posterior to anterior axis. Although the most striking developmental changes in response to testosterone were observed in the three layers of the comb dermis, some change was also noted in the mucopolysaccharidal development of the outermost epidermal layers. |
| General note | Submitted to the faculty of the Department of Biology. |
| General note | Advisor: Irvin E. Lawrence, Jr. |
| Dissertation note | M.A. East Carolina University 1968 |
| Bibliography note | Includes bibliographical references (leaves 47-49). |
| Genre/form | dissertations. |
| Genre/form | Academic theses. |
| Genre/form | Academic theses. |
| Genre/form | Thèses et écrits académiques. |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Joyner | University Archives | ASK AT SPECIAL COLLECTIONS DESK | ✔ Available | Request Material |
| Electronic Resources | Access Content Online | ✔ Available |