The induction of consecutive pseudopregnancies by estrogen-progesterone injections in the mature albino rat, Rattus norvegicus (Berkenhout) / by Michael Reed Garrett.
| Author/creator | Garrett, Michael Reed, 1943- author. |
| Other author | Simpson, Everett C., degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Production | 1967. |
| Description | 40 leaves ; 28 cm |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | In 10 untreated control rats of the Holtzman strain, two consecutive periods of pseudopregnancy were not induced by cervical stimulation. The administration of estrogen-progesterone injections to 30 experimental rats was begun on the twelfth or thirteenth day of the first pseudopregnancy, and this pseudopregnancy was extended. The longest extended first pseudopregnancy was exhibited in rats that received hormonal injections beginning on day 12. Consecutive pseudopregnancies were induced only when first pseudopregnancies were dependent upon intervals at which hormones were given during second pseudopregnancies. Investigation of ovaries of rats in a first pseudopregnancy as compared to those in a second consecutive pseudopregnancy, showed no significant difference between the numbers of corpora lutea observed in each group. There was however, a significant reduction in the corpora lutea of control rats which were not induced into a second consecutive pseudopregnancy. This was thought to have resulted in an insufficiency of gonadal hormones, and it was hypothesized that this insufficiency prevented the induction of a second consecutive pseudopregnancy in the control animals. |
| General note | Submitted to the faculty of the Department of Biology. |
| General note | Advisor: Everett C. Simpson |
| Dissertation note | M.A. East Carolina University 1967 |
| Bibliography note | Includes bibliographical references (leaves 38-40). |
| Genre/form | dissertations. |
| Genre/form | Academic theses. |
| Genre/form | Academic theses. |
| Genre/form | Thèses et écrits académiques. |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Joyner | University Archives | ASK AT SPECIAL COLLECTIONS DESK | ✔ Available | Request Material |
| Electronic Resources | ✔ Available |