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020 a| 9780470414118 (cloth);

020 a| 0470414111 (cloth);

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100 1 a| Stein, Ross L.?| UNAUTHORIZED;

245 10 a| Kinetics of enzyme actionh| [electronic resource] :b| essential principles for drug hunters /c| Ross L. Stein.;

260 a| Hoboken, N.J. :b| John Wiley,;

300 a| xii, 302 p. :b| ill. ;c| 25 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| Kinetics of single-substrate enzymatic reactions -- Kinetics of single-substrate enzymatic reactions : special topics -- Enzyme inhibition : the phenomenon and mechanistic analysis -- Kinetic mechanism of inhibition of one-substrate enzymatic reactions -- Tight-binding, slow-binding, and irreversible inhibitors -- Kinetics of two-substrate enzymatic reactions -- Kinetic mechanism of inhibition of two-substrate enzymatic reactions -- Allosteric modulation of enzyme-catalyzed reactions -- Kinetics-based probes of enzyme mechanisms.;

506 a| Available only to authorized users.;

520 a| "Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery"--Provided by publisher.;

538 a| Mode of access: World Wide Web;

650 0 a| Enzymesx| Pharmacokinetics.=| ^A458;

650 0 a| Enzyme inhibitorsx| Pharmacokinetics.=| ^A13189;

650 12 a| Enzymesx| pharmacokinetics.=| ^A919456;

650 22 a| Drug Discovery.=| ^A1013013;

650 22 a| Enzyme Activation.=| ^A950895;

650 22 a| Enzyme Inhibitorsx| pharmacokinetics.=| ^A921875;

655 0 a| Electronic books.=| ^A491897;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=693195;

947 a| (OCoLC)ocn703208265;

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Kinetics of enzyme action essential principles for drug hunters / Ross L. Stein.

Author/creator	Stein, Ross L.
Format	Electronic
Publication Info	Hoboken, N.J. : John Wiley,
Description	xii, 302 p. : ill. ; 25 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Enzymes--Pharmacokinetics. Enzyme inhibitors--Pharmacokinetics. Enzymes--pharmacokinetics. Drug Discovery. Enzyme Activation. Enzyme Inhibitors--pharmacokinetics.

Contents	Kinetics of single-substrate enzymatic reactions -- Kinetics of single-substrate enzymatic reactions : special topics -- Enzyme inhibition : the phenomenon and mechanistic analysis -- Kinetic mechanism of inhibition of one-substrate enzymatic reactions -- Tight-binding, slow-binding, and irreversible inhibitors -- Kinetics of two-substrate enzymatic reactions -- Kinetic mechanism of inhibition of two-substrate enzymatic reactions -- Allosteric modulation of enzyme-catalyzed reactions -- Kinetics-based probes of enzyme mechanisms.
Abstract	"Few scientists have the knowledge to perform the studies that are necessary to discover and characterize enzyme inhibitors, despite the vested interest the pharmaceutical industry has in this field. Beginning with the most basic principles pertaining to simple, one-substrate enzyme reactions and their inhibitors, and progressing to a thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical scientists with numerous case study examples to outline the tools and techniques necessary to perform, understand, and interpret detailed kinetic studies for drug discovery"--Provided by publisher.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2011015205
ISBN	9780470414118 (cloth)
ISBN	0470414111 (cloth)

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