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010 a| 2008029607;

016 7 a| 1014781472| DNLM;

020 a| 9780470412893 (cloth);

020 a| 0470412895 (cloth);

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245 00 a| Gene family targeted molecular designh| [electronic resource] /c| edited by Karen E. Lackey.;

260 a| Hoboken, N.J. :b| John Wiley & Sons,;

300 a| xvi, 347 p., [16] p. of plates :b| ill. (some col.) ;c| 25 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams ... [et al.] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Pharmacogenomics.=| ^A881910;

650 0 a| Drugsx| Design.=| ^A477567;

650 12 a| Drug Design.=| ^A925973;

650 22 a| Genes.=| ^A920282;

650 22 a| Ion Channelsx| genetics.=| ^A1203096;

650 22 a| Models, Molecular.=| ^A933130;

650 22 a| Pharmacogeneticsx| methods.=| ^A939790;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Lackey, Karen.?| UNAUTHORIZED;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=406459;

947 a| (OCoLC)233678601;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4093303-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 1/1/2016x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4093303-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 1/1/2016x| EBOOKz| JERESOURCE;

Gene family targeted molecular design / edited by Karen E. Lackey.

Other author	Lackey, Karen.
Format	Electronic
Publication Info	Hoboken, N.J. : John Wiley & Sons,
Description	xvi, 347 p., [16] p. of plates : ill. (some col.) ; 25 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Pharmacogenomics. Drugs--Design. Drug Design. Genes. Ion Channels--genetics. Models, Molecular. Pharmacogenetics--methods.

Contents	Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. Heightman -- Ion channels gene family : strategies for discovering ion channel drugs / Maria L. Garcia and Gregory J. Kaczorowski -- Integrins / David D. Miller -- Strategies for discovering kinase drugs / Jerry L. Adams ... [et al.] -- Protease-directed drug discovery / Richard Sedrani, Ulrich Hommel, and Jor̈g Eder -- Small-molecule inhibitors of protein-protein interactions : challenges and prospects / Adrian Whitty -- Transporters / Anne Hersey, Frank E. Blaney, and Sandeep Modi -- Nuclear receptor drug discovery / Hiroyuki Kagechika and Aya Tanatani -- Summary and comparison of molecules designed to modulate druggable targets in the major gene families / Karen E. Lackey.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2008029607
ISBN	9780470412893 (cloth)
ISBN	0470412895 (cloth)

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Gene family targeted molecular design / edited by Karen E. Lackey.

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