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010 a| 2010028355;

020 a| 9780470499467 (cloth);

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245 00 a| Gene discovery for disease modelsh| [electronic resource] /c| edited by Weikuan Gu and Yongjun Wang.;

260 a| Hoboken, N.J. :b| Wiley,;

300 a| xiii, 537 p., [16] p. of plates :b| ill. (some col.) ;c| 25 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| Introduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Medical genetics.=| ^A874;

650 0 a| Mutation (Biology)=| ^A2390;

650 0 a| Genomics.=| ^A528942;

650 0 a| Genetic disorders.=| ^A311977;

650 12 a| Genetic Association Studiesx| methods.=| ^A1037991;

650 22 a| Models, Genetic.=| ^A927393;

650 22 a| Mutation.=| ^A917789;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Gu, Weikuan.=| ^A1039876;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=661512;

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Gene discovery for disease models / edited by Weikuan Gu and Yongjun Wang.

Other author	Gu, Weikuan.
Format	Electronic
Publication Info	Hoboken, N.J. : Wiley,
Description	xiii, 537 p., [16] p. of plates : ill. (some col.) ; 25 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Medical genetics. Mutation (Biology) Genomics. Genetic disorders. Genetic Association Studies--methods. Models, Genetic. Mutation.

Contents	Introduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2010028355
ISBN	9780470499467 (cloth)

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Gene discovery for disease models / edited by Weikuan Gu and Yongjun Wang.

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