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020 a| 0121479528 (acid-free paper);

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100 1 a| Butler, John M.q| (John Marshall),d| 1969-=| ^A503644;

245 10 a| Forensic DNA typingh| [electronic resource] :b| biology, technology, and genetics of STR markers /c| John M. Butler.;

250 a| 2nd ed.;

260 a| Amsterdam ;a| Boston :b| Elsevier Academic Press,;

300 a| xvii, 660 p. :b| ill. (some col.) ;c| 26 cm.;

504 a| Includes bibliographical references and indexes.;

505 00 t| Overview and history of DNA typing --t| DNA biology review --t| Sample collection, DNA extraction and DNA quantitation --t| The polymerase chain reaction (DNA amplification) --t| Commonly used short tandem repeat markers and commercial kits --t| Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates --t| Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number --t| Single nucleotide polymorphisms and other bi-allelic markers -- Y chromosome DNA testing -- Mitochondrial DNA analysis -- Non-human DNA testing and microbial forensics --t| DNA separation methods : slab-gel and capillary electrophoresis --t| DNA detection methods : fluorescent dyes and silver-staining --t| Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems --t| STR genotyping issues --t| Laboratory validation --t| New technologies, automation, and expert systems --t| Combined DNA index system (CODIS) and the use of DNA databases --t| Basic genetic principles, statistics, and probability -- STR population database analyses -- Profile frequency estimates, likelihood ratios, and source attribution -- Approaches to statistical analysis of mixtures and degraded DNA -- Kinship and parentage testing -- Mass disaster DNA victim identification.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| DNA fingerprinting.=| ^A427935;

650 0 a| Forensic genetics.=| ^A359167;

650 0 a| DNAx| Synthesis.=| ^A633;

650 12 a| DNA Fingerprintingx| methods.=| ^A926654;

650 22 a| Databases, Nucleic Acid.=| ^A1407834;

650 22 a| Forensic Medicine.=| ^A918151;

655 0 a| Electronic books.=| ^A491897;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=286691;

947 a| (OCoLC)ocm58844928;

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Forensic DNA typing biology, technology, and genetics of STR markers / John M. Butler.

Author/creator	Butler, John M., 1969-
Format	Electronic
Edition	2nd ed.
Publication Info	Amsterdam ; Boston : Elsevier Academic Press,
Description	xvii, 660 p. : ill. (some col.) ; 26 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	DNA fingerprinting. Forensic genetics. DNA--Synthesis. DNA Fingerprinting--methods. Databases, Nucleic Acid. Forensic Medicine.

Contents	Overview and history of DNA typing -- DNA biology review -- Sample collection, DNA extraction and DNA quantitation -- The polymerase chain reaction (DNA amplification) -- Commonly used short tandem repeat markers and commercial kits -- Biology of STRs : stutter products, non-template addition, microvariants, null alleles, and mutation rates -- Forensic issues : degraded DNA, PCR inhibition, contamination, mixed samples and low copy number -- Single nucleotide polymorphisms and other bi-allelic markers -- Y chromosome DNA testing -- Mitochondrial DNA analysis -- Non-human DNA testing and microbial forensics -- DNA separation methods : slab-gel and capillary electrophoresis -- DNA detection methods : fluorescent dyes and silver-staining -- Instrumentation for STR typing : ABI 310, ABI 3100, FMBIO systems -- STR genotyping issues -- Laboratory validation -- New technologies, automation, and expert systems -- Combined DNA index system (CODIS) and the use of DNA databases -- Basic genetic principles, statistics, and probability -- STR population database analyses -- Profile frequency estimates, likelihood ratios, and source attribution -- Approaches to statistical analysis of mixtures and degraded DNA -- Kinship and parentage testing -- Mass disaster DNA victim identification.
Bibliography note	Includes bibliographical references and indexes.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2004114214
ISBN	0121479528 (acid-free paper)

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Forensic DNA typing biology, technology, and genetics of STR markers / John M. Butler.

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