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245 00 a| Evaluation of drug candidates for preclinical developmenth| [electronic resource] :b| pharmacokinetics, metabolism, pharmaceutics, and toxicology /c| edited by Chao Han, Charles B. Davis, Binghe Wang.;

260 a| Hoboken, N.J. :b| John Wiley & Sons,;

300 a| x, 289 p., [2] p. of plates :b| ill. (some col.) ;c| 25 cm.;

490 0 a| Wiley series in drug discovery and development;

504 a| Includes bibliographical references and index.;

505 0 a| Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Drug development.=| ^A443888;

650 0 a| Pharmacokinetics.=| ^A2311;

650 0 a| Drugsx| Metabolism.=| ^A3641;

650 12 a| Drug Evaluation, Preclinical.=| ^A938316;

650 22 a| Drug Discovery.=| ^A1013013;

650 22 a| Drug Industryx| standards.=| ^A919097;

650 22 a| Pharmaceutical Preparationsx| metabolism.=| ^A933588;

650 22 a| Pharmacologyx| methods.=| ^A923438;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Han, Chao.?| UNAUTHORIZED;

700 1 a| Davis, Charles B.q| (Charles Baldwin)?| UNAUTHORIZED;

700 1 a| Wang, Binghe,d| 1962-?| UNAUTHORIZED;

856 40 z| Full text available from Books@Ovid - Wiley Essentials in Pharmaceutical Science Book Collectionu| https://go.openathens.net/redirector/ecu.edu?url=http%3A%2F%2Fovidsp.ovid.com%2Fovidweb.cgi%3FT%3DJS%26NEWS%3Dn%26CSC%3DY%26PAGE%3Dbooktext%26D%3Dbooks%26AN%3D01439066%24%26XPATH%3D%2FPG%280%29;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=479843;

947 a| (OCoLC)ocn435728364;

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Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology / edited by Chao Han, Charles B. Davis, Binghe Wang.

Other author	Han, Chao.
Other author	Davis, Charles B. (Charles Baldwin)
Other author	Wang, Binghe, 1962-
Format	Electronic
Publication Info	Hoboken, N.J. : John Wiley & Sons,
Description	x, 289 p., [2] p. of plates : ill. (some col.) ; 25 cm.
Supplemental Content	Full text available from Books@Ovid - Wiley Essentials in Pharmaceutical Science Book Collection
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Drug development. Pharmacokinetics. Drugs--Metabolism. Drug Evaluation, Preclinical. Drug Discovery. Drug Industry--standards. Pharmaceutical Preparations--metabolism. Pharmacology--methods.

Series	Wiley series in drug discovery and development
Contents	Pharmacokinetics in preclinical drug development : an overview / Dion Brocks -- The role of membrane transporters in drug disposition / Fanfan Zhou, Peng Duan, and Guofeng You -- Cytochrome P450 : structure, function, and application in drug discovery and development / Ramesh B. Bambal and Stephen E. Clarke -- The role of drug metabolism and metabolite identification in drug discovery / Xiangming Guan -- Protein binding in drug discovery and development / Vikram Ramanathan and Nimish Vachharajani -- Prediction of the pharmacokinetics in humans / Chao Han and Ramesh Bambal -- Pharmaceutics developability assessment / Lian Huang, Jinquan Dong, and Shyam Karki -- Safety assessment in drug discovery / Vito G. Sasseville, William R. Foster, and Bruce D. Car -- Assessment of strategies utilized to minimize the potential for induction of acquired long QT syndrome and torsade de pointes / Khuram W. Chaudhary and Barry S. Brown.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2009035876
ISBN	9780470044919 (cloth)

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Library	Location	Call Number	Status	Item Actions
	Electronic Resources	Online Content Full text available from Books@Ovid - Wiley Essentials in Pharmaceutical Science Book Collection Full text available from Ebook Central - Academic Complete	✔ Available

Evaluation of drug candidates for preclinical development pharmacokinetics, metabolism, pharmaceutics, and toxicology / edited by Chao Han, Charles B. Davis, Binghe Wang.

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