Biotransformation and metabolite elucidation of xenobiotics / edited by Ala F. Nassar.

Other author Nassar, Ala F.
Format Electronic
Publication InfoHoboken, N.J. : John Wiley & Sons,
Descriptionxi, 328 p. : ill. ; 25 cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

Contents Human biotransformation / Andrew Parkinson -- Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li -- Tools of choice for accelerating metabolite identification : mass spec technology drives metabolite identification studies forward / Ala Nassar -- Improving drug design : considerations for the structural modification process / Ala Nassar -- Case study : the unanticipated loss of N2 from novel dna alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala Nassar, Tukiet T. Lam -- Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala Nassar, TuKiet T. Lam -- Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo -- Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2010016629
ISBN9780470504789 (cloth)

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