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020 a| 9780470449820 (cloth);

020 a| 0470449829 (cloth);

020 a| 9781118001042 (oBook);

020 a| 1118001044 (oBook);

020 a| 9781118008980 (ePub);

020 a| 1118008987 (ePub);

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245 00 a| Applications of toxicogenomics in safety evaluation and risk assessmenth| [electronic resource] /c| edited by Darrell R. Boverhof, B. Bhaskar Gollapudi.;

260 a| Hoboken, N.J. :b| John Wiley & Sons,;

300 a| xiii, 377 p. :b| ill. (some col.) ;c| 25 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment -- early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation -- activities in Japan -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Genetic toxicology.=| ^A215858;

650 0 a| Toxicity testing.=| ^A14420;

650 0 a| Health risk assessment.=| ^A166224;

650 12 a| Toxicogenetics.=| ^A941474;

650 22 a| Risk Assessment.=| ^A929045;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Boverhof, Darrell R.?| UNAUTHORIZED;

700 1 a| Gollapudi, B. Bhaskar.?| UNAUTHORIZED;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=693202;

947 a| (OCoLC)ocn671385938;

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Applications of toxicogenomics in safety evaluation and risk assessment / edited by Darrell R. Boverhof, B. Bhaskar Gollapudi.

Other author	Boverhof, Darrell R.
Other author	Gollapudi, B. Bhaskar.
Format	Electronic
Publication Info	Hoboken, N.J. : John Wiley & Sons,
Description	xiii, 377 p. : ill. (some col.) ; 25 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Genetic toxicology. Toxicity testing. Health risk assessment. Toxicogenetics. Risk Assessment.

Contents	Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment -- early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation -- activities in Japan -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2010043286
ISBN	9780470449820 (cloth)
ISBN	0470449829 (cloth)
ISBN	9781118001042 (oBook)
ISBN	1118001044 (oBook)
ISBN	9781118008980 (ePub)
ISBN	1118008987 (ePub)

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Applications of toxicogenomics in safety evaluation and risk assessment / edited by Darrell R. Boverhof, B. Bhaskar Gollapudi.

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