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LEADER 03439ctm a2200505 i 4500

001 ocm20450081;

003 OCoLC;

005 20231106090626.0;

008 891006s1988 xx a bm 000 0 eng d;

035 a| (Sirsi) o20450081;

035 a| (OCoLC)20450081;

049 a| EREE;

050 4 a| RG629.F45b| B82x 1988;

100 1 a| Buckenmaier, Chester,c| III,e| author.=| ^A995738;

245 10 a| Uterus/oviduct luminal levels of ethanol and acetaldehyde in relation to blood levels of these compounds and their effects on pre-implantation 2-cell stage mouse embryos in vitro /c| by Chester Buckenmaier III.;

264 0 c| 1988.;

300 a| iv pages, 49 unnumbered leaves :b| 17 illustrations ;c| 28 cm;

336 a| textb| txt2| rdacontent;

337 a| unmediatedb| n2| rdamedia;

338 a| volumeb| nc2| rdacarrier;

502 b| M.S.c| East Carolina Universityd| 1988;

500 a| Submitted to the faculty of the Department of Biology.;

500 a| Advisor: Gerhard W. Kalmus;

520 3 a| CF-l mice were injected intraperitoneally with 0.02 ml/gm body weight of a 25X ethanol in saline solution. Ethanol and acetaldehyde levels, in blood and the uterine/oviducal lumen, were monitored for three hours. Uterine/oviducal luminal ethanol levels were closely associated with blood ethanol levels, since both concentrations dropped over a three hour time period. Uterine/oviducal and blood acetaldehyde data was inconclusive. In addition, CF-l mouse 2-cell stage embryos were exposed to ethanol (200-600 mg ethanol/100 ml medium) and acetaldehyde (5-500 mg acetaldehyde/100 ml medium) for 60 min. in vitro, and then maintained in culture for 105 hours. Embryos treated with ethanol concentrations as high as 600 mg/100 ml medium or acetaldehyde levels up to 10 mg/100 ml medium survived equally well as control embryos cultured in medium alone. These data suggest that ethanol and acetaldehyde may not directly affect pre-implantation embryos.;

504 a| Includes bibliographical references (leaves 38-41).;

650 0 a| Fetal alcohol spectrum disorders.=| ^A9833;

650 2 a| Fetal Alcohol Spectrum Disorders0| (DNLM)D063647=| ^A1205587;

655 2 a| Academic Dissertation.0| (DNLM)D019478?| UNAUTHORIZED;

650 7 a| Fetal alcohol spectrum disorders.2| fast0| (OCoLC)fst00923356;

655 7 a| Academic theses.2| fast0| (OCoLC)fst01726453;

655 7 a| Academic theses.2| lcgft;

655 7 a| Thèses et écrits académiques.2| rvmgf0| (CaQQLa)RVMGF-000001173;

700 1 a| Kalmus, Gerhard W.,e| degree supervisor.?| UNAUTHORIZED;

710 2 a| East Carolina University.b| Department of Biology.=| ^A637467;

856 40 z| Access via ScholarShipu| http://hdl.handle.net/10342/11886;

949 a| Click on web addressw| asish| joyner101;

949 a| Click on web addressw| asish| hsl111;

994 a| C0b| ERE;

596 a| 1 4;

998 a| 327818;

999 a| MICROFILMw| JMFc| 1i| 218496*l| JMFOTm| JOYNERr| Ys| Yt| JMFOTFIu| 11/6/1989x| MICROFORMz| JMICROFORMo| .STAFF. 0;

999 a| ASK AT SPECIAL COLLECTIONS DESKw| ASISc| 1i| 491796d| 6/14/2001l| JSCJTHDm| JOYNERr| Ys| Yt| JSCJTHDu| 6/14/2001x| ETDz| JSPECCOLLo| .STAFF. 0;

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Uterus/oviduct luminal levels of ethanol and acetaldehyde in relation to blood levels of these compounds and their effects on pre-implantation 2-cell stage mouse embryos in vitro / by Chester Buckenmaier III.

Author/creator	Buckenmaier, Chester author.
Other author	Kalmus, Gerhard W., degree supervisor.
Other author	East Carolina University. Department of Biology.
Format	Theses and dissertations
Production	1988.
Description	iv pages, 49 unnumbered leaves : 17 illustrations ; 28 cm
Supplemental Content	Access via ScholarShip
Subjects	Fetal alcohol spectrum disorders. Fetal Alcohol Spectrum Disorders

Summary	CF-l mice were injected intraperitoneally with 0.02 ml/gm body weight of a 25X ethanol in saline solution. Ethanol and acetaldehyde levels, in blood and the uterine/oviducal lumen, were monitored for three hours. Uterine/oviducal luminal ethanol levels were closely associated with blood ethanol levels, since both concentrations dropped over a three hour time period. Uterine/oviducal and blood acetaldehyde data was inconclusive. In addition, CF-l mouse 2-cell stage embryos were exposed to ethanol (200-600 mg ethanol/100 ml medium) and acetaldehyde (5-500 mg acetaldehyde/100 ml medium) for 60 min. in vitro, and then maintained in culture for 105 hours. Embryos treated with ethanol concentrations as high as 600 mg/100 ml medium or acetaldehyde levels up to 10 mg/100 ml medium survived equally well as control embryos cultured in medium alone. These data suggest that ethanol and acetaldehyde may not directly affect pre-implantation embryos.
General note	Submitted to the faculty of the Department of Biology.
General note	Advisor: Gerhard W. Kalmus
Dissertation note	M.S. East Carolina University 1988
Bibliography note	Includes bibliographical references (leaves 38-41).
Genre/form	Academic theses.
Genre/form	Academic theses.
Genre/form	Thèses et écrits académiques.

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Uterus/oviduct luminal levels of ethanol and acetaldehyde in relation to blood levels of these compounds and their effects on pre-implantation 2-cell stage mouse embryos in vitro / by Chester Buckenmaier III.

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