Zinc concentrations in select tissues from actute alloxan-diabetic male rates / by Kent D. Slemmons.
| Author/creator | Slemmons, Kent D. author. |
| Other author | McNeill, M. Evelyn, degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Production | 1983. |
| Description | vi, 51 leaves : illustrations ; 28 cm |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | Current evidence suggests that the diabetic condition may be accompanied by alterations in zinc metabolism. This study compared the zinc levels in select tissues from acute alloxan-diabetic and normal adult male rats. Of particular interest were tissues associated with reproduction and the complications of diabetes mellitus. Experimental diabetes was induced in male Sprague-Dawley rats by intravenous alloxan injection (40 mg/kg body weight). Four weeks after alloxan administration, tissue zinc levels were determined by atomic absorption spectrophotometry. Zinc concentrations were significantly higher in the adenohypophysis (P[less-than] 0.03), brain (P[less-than]0.03), and prostate (P[less-than] 0.01) of the diabetic group. Zinc concentrations in the lens, retina, pineal, neurohypophysis, hypothalamus, aorta, liver, kidney, and pancreas were similar to controls. These results, along with the results of other studies (Failla and Kiser, 1981; McNeill et al., 1981), suggest that experimental diabetes results in a buildup of zinc in select tissues. |
| General note | "Presented to the faculty of the Department of Biology ... in partial fulfillment of the requirements for the degree Master of Science in Biology." |
| General note | Advisor: M. Evelyn McNeill |
| Dissertation note | M.S. East Carolina University 1983 |
| Bibliography note | Includes bibliographical references (leaves 39-46). |
| Funding information | "Supported in part by United Way Grant 0-58026 and Mary C. Helms Research Grant." |
| Genre/form | dissertations. |
| Genre/form | Academic theses. |
| Genre/form | Academic theses. |
| Genre/form | Thèses et écrits académiques. |
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